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Results for "ion chamber": 59 found

A 2D Discrete Ionization Chamber Array for Proton Pencil Beam Scanning Flash Dosimetry

Authors: Fu-Xiong Chang, Arpit M. Chhabra, J Isabelle Choi, Chanda Guha, Nancy Y Lee, Chih-Hsun Lin, Haibo Lin, Hang Qi, Mahbubur Rahman, Charles B. Simone, Pingfang Tsai, Shouyi Wei, Irini Yacoub, Yunjie Yang, Ajay Zheng, Jun Zhou

Affiliation: New York Proton Center, Montefiore Medical Center and Albert Einstein College of Medicine, Liverage Biomedical Inc., Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology and Winship Cancer Institute, Emory University, Institute of Physics, Academia Sinica

Abstract Preview: Purpose: FLASH therapy presents an opportunity to alter the radiotherapy paradigm and significantly enhancing normal organ protection while maintaining the effectiveness of tumor control. The temporal...

A 3D Printed Ion Chamber Insert Solution for Absolute Dosimetry with Varying Ionisation Chambers in Radiosurgery.

Authors: Shashanksharad Kale, Gopishankar Natanasabapathi, Daya Nand Kishore Sharma

Affiliation: All India Institute of Medical Sciences (AIIMS), Department of Radiation Oncology, All India Institute of Medical Sciences

Abstract Preview: Purpose:
The study demonstrates a novel 3D printing method to fabricate an ion chamber insert (ICI) for absolute dosimetry purpose in gamma knife radiosurgery (GKRS).
Methods:
Our institute u...

A Beagle Dog Mesh-Type Phantom for Application to Nuclear Medicine and Internal Dosimetry

Authors: Wesley E. Bolch, Natalia Estefania Carrasco-Rojas, Chansoo Choi, Robert Joseph Dawson, Aitor Gallastegui Menoyo, Rowan James Milner, Bangho Shin, Maria M. Von Chamier

Affiliation: University of Florida

Abstract Preview: Purpose: To develop a tetrahedralizable mesh-type phantom of a male beagle dog to later perform Monte Carlo radiation transport simulations and calculate organ doses using monoenergetic photons, elect...

A GPU Accelerated Monte Carlo Dose Engine for Small Animal Proton Radiotherapy

Authors: Haonian Gong, Yue Gu, Meiqi Liu, Zihao Liu, Hsiao-Ming Lu, Yuxiang Wang, Yidong Yang, Cheng Zheng

Affiliation: Hefei Ion Medical Center, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Department of Engineering and Applied Physics, University of Science and Technology of China, University of Science and Technology of China

Abstract Preview: Purpose:
Proton radiotherapy in preclinical small animals requires specific dose engine due to its low energy and small irradiation volume. This study is to develop a GPU-based Monte Carlo dose eng...

A Perturbative Approach to Determine the Charge Collection Efficiency in High Dose-per-Pulse Beams

Authors: Julien Bancheri, Jan P. Seuntjens

Affiliation: Medical Biophysics, University of Toronto, Princess Margaret Cancer Centre & University of Toronto

Abstract Preview: Purpose: To obtain an analytical expression for the charge collection efficiency of parallel-plate ionization chambers in high dose-per-pulse (DPP) beams that takes into account the square pulse time ...

Absolute Measurement of HDR Ir-192 Air-Kerma Strength Using an Exradin A3 Known-Volume Ionization Chamber

Authors: Larry A. DeWerd, Sean Jollota, Karen Rex Pius Vincent

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison

Abstract Preview: Purpose: Absolute measurements, often used to establish primary standards, offer lower measurement uncertainty. For 192Ir high-dose-rate (HDR) brachytherapy, the interim primary standard for air-kerma...

Addressing Radionuclide Decay Complexities in Targeted Alpha Therapy: A Computational Approach.

Authors: Denis Bergeron, Ryan P Fitzgerald, Ravneet Kaur, Rao Khan

Affiliation: John Hopkins University, NIST Radiation Physics Division, Howard University, National Institute of Standards and Technology

Abstract Preview: Purpose: There is growing interest in short-lived alpha-emitting radionuclides for cancer therapy due to their ability to selectively target and destroy cancer cells while sparing healthy tissue. Howe...

Advancing Flash Radiotherapy: Intercomparison of Parameters between Two Institutions to Optimize Clinical Applications.

Authors: Amir Abdollahi, Celine Karle, Michele M. Kim, Constantinos Koumenis, Andrea Mairani, Erato Stylianou Markidou

Affiliation: Heidelberg Ion-Beam Therapy Center - Department of Radiation Oncology, German Cancer Research Centre(DKFZ), University of Pennsylvania, Physics Dep. University of Cyprus

Abstract Preview: Purpose: The aim is to compare FLASH dose-rate RT generated with protons and carbon (HIT) and compare to protons (UPenn) to provide evidence for equipotency of FLASH vs. standard RT to tumor growth co...

An Evaluation of an SRS Quality Assurance System for Complex Patient Plans.

Authors: John Bennet, Indrin J. Chetty, Tai H. Dou

Affiliation: Department of Radiation Oncology,Cedars Sinai Medical Center, Department of Radiation Oncology, Cedars Sinai Medical Center, Department of Radiation Oncology,Cedars-Sinai Medical Center

Abstract Preview: Purpose:
To investigate the effect of complexity of stereotactic radiosurgery (SRS) volumetric modulated arc therapy plans on gamma pass rates (GPR) using a novel high-resolution ion chamber array ...

Assessment of the Dosimetric Characteristics of Brass Mesh Bolus in Electron Radiation Therapy

Authors: Hungcheng Hank Chen, Laura A. Doyle, Helena Frisbie-Firsching, Amy S. Harrison, Jackson D Reeves, Lindsay B Romak, Jon Strasser

Affiliation: Christiana Care

Abstract Preview: Purpose: Brass mesh bolus (BMB) is a high-density woven metal mesh which is an excellent alternative to tissue equivalent bolus in photon beams, offering improved surface conformality. Unlike utilizat...

Auto-Beam Hold Validation for Varian Sgrt Identify 3.0 on Truebeam Linear Accelerators

Authors: Hongyu Jiang, Wangyao Li, Dima Soultan, Fen Wang, Jun Xu

Affiliation: Department of Radiation Oncology, University of Kansas Medical Center

Abstract Preview: Purpose: To validate the Auto-Beam Hold functionality via the MMI connection between Varian SGRT system IDENTIFY 3.0 and treatment linacs.
Methods: A treatment plan was created in the Eclipse TPS u...

Characterization of Commercially-Available Dosimeters and Prototype Diamond Detectors for Absolute Flash Dosimetry of Small-Field Pulsed Proton Beams

Authors: Ronald C Chen, Hao Gao, Nicolas Gerard, Harold Li, Yuting Lin, Jarrick Nys, Jufri Setianegara, Mark Szczepanski, Aoxiang Wang

Affiliation: 4Physikalisch-Technische Werkstätten (PTW), Department of Biomedical Engineering, Huazhong University of Science and Technology, Ion Beam Applications (IBA), Department of Radiation Oncology, University of Kansas Medical Center

Abstract Preview: Purpose: Modern synchrocyclotrons can produce magnetically-scanned protons at ultra-high dose-rates (FLASH). However, their pulsed nature leads to high doses-per-pulse (DPP) which can cause non-neglig...

Characterizing and Modeling Higher-Order Motions of Collimator Subsystem on a 60RPM Gantry Linac for Improved Small Target Dosimetry

Authors: David J. Carlson, Yiu-Hsin Chang, Huixiao Chen, Zhe (Jay) Chen, Blake Gaderlund, Ray Yang

Affiliation: RefleXion Medical, Department of Therapeutic Radiology, Yale University School of Medicine

Abstract Preview: Purpose: To address the root cause of dosimetric discrepancy for small central targets (<2cm) especially sensitive to geometric alignment of beamlets, by modeling higher-order oscillations of the coll...

Commissioning a Fixed Beamline Ultra-High Dose Rate Proton Therapy System

Authors: Ahmet S. Ayan, Austin M. Faught, Eunsin Lee, Julia Pakela

Affiliation: Department of Radiation Oncology, The Ohio State University Wexner Medical Center, Ohio State University, The Ohio State University

Abstract Preview: Purpose: To present commissioning of a fixed beamline ultra-high dose rate proton pencil beam scanning system, the world’s first multi-room Varian ProBeam360⁰
Methods: The fixed beamline pencil bea...

Commissioning, Validation and Pilot Study of New Rpld System for Dosimetry Audits in Bulgaria

Authors: Gueorgui Gueorguiev, Katia Sergieva, Filip Simeonov, Tsvetelina Todorova, Bozhidar Vladimirov

Affiliation: National Centre of Radiobiology and Radiation Protection, Queen Giovanna University Hospital

Abstract Preview: Purpose: Dosimetry audit is an essential tool enhancing confidence in the accuracy of treatment delivery and in prevention of radiation treatment incidents. Current work depicts how novel nationwide r...

Comparison Analysis of Three Kind of Solutions for Head and Neck Cancer VMAT Verification

Authors: Wenwen Bai

Affiliation: The Fourth Hospital of Hebei Medical University

Abstract Preview: Purpose: To compare three kind of solutions (EDR2 Film, MatriXX, COMPASS) for VMA quality assurance at head and Neck in Monaco plannig system.
Methods: Monacao 5.1 planning system optimazed 10 case...

Design and Testing of an External Control System for Beam Control and Pre-Delivery Optimization for Conventional- and Ultra-High-Dose-per-Pulse Flash Irradiations

Authors: Alexander Baikalov, Luke Connell, Nicholas Coupey, Nolan M. Esplen, Rebecca Lim, Chinh Nguyen, Emil Schueler

Affiliation: Northwell, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center

Abstract Preview: Purpose: FLASH radiotherapy delivered using electron linear accelerators (LINAC) requires precise control and minimal variation of dose rate and We developed a robust external beam control system (EBC...

Development of a Novel 3D-Printed Heterogeneous Phantom for Liver SBRT Dose Verification in Hepatocellular Carcinoma (HCC) Treatment.

Authors: Dr. Sheaka Alobaidli, Anju K V, Dr. Chiranjib Konar, Sreejesh MS, Dr. Vijayaprabhu N, Dr. Deepti Sharma, Dr. Hanuman Prasad Yadav

Affiliation: Amity Institute of Applied Sciences, Kuwait Cancer Control Center, Institute of Liver and Biliary Sciences, Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Amity institute of Applied Sciences, Amity University, Institute of Liver and Biliary Sciences(ILBS)

Abstract Preview: Purpose:
The accuracy of dose delivery in stereotactic body radiotherapy (SBRT) is critical for effectively treating hepatocellular carcinoma (HCC). This study aims to develop patient-specific 3D-p...

Dose Rate Measurements of Scanning Carbon Ion Beams Using a Plastic Scintillator Detector

Authors: Motohiro Kawashima, Adrian Kugara, Masao Nakao, Shuichi Ozawa, Mutsumi Tashiro, Maria Varnava

Affiliation: Gunma University Heavy Ion Medical Center, Hiroshima High-Precision Radiotherapy Cancer Center

Abstract Preview: Purpose: This study aimed to evaluate the time-dependent dose rate characteristics of a scanning carbon ion beam using a fast-response plastic scintillator detector (PSD), with a focus on its potentia...

Dosimeteric Parameter Evaluation of Digital Polycrystalline Semiconductor Dosimeters for Quality Assurance of High-Dose-Rate Brachytherapy

Authors: Woong Cho, Jin-Beom Chung, Moo-Jae Han, Sang Won Kang, Boram Lee

Affiliation: Department of Radiation Oncology, Seoul National University Boramae Medical Center, Department of Radiation Oncology, Seoul National University Bundang Hospital, Department of Radiation Oncology, Inha University Hospital

Abstract Preview: Purpose: This study aims to establish a digital quality assurance (QA) system for high-dose-rate (HDR) brachytherapy by evaluating self-developed polycrystalline semiconductor dosimeters (PSDs).
Me...

Dosimetric Accuracy Evaluation of Brainlab Elements 4.0 Treatment Planning System

Authors: Bhuvaneswari Narayanan, Niko Papanikolaou, Daniel L. Saenz

Affiliation: UT Health San Antonio, University of Texas HSC San Antonio

Abstract Preview: Purpose: To evaluate dosimetric accuracy of Brainlab Elements (BLE) 4.0 treatment planning system (TPS) for linac based SRS and Spine SBRT treatment.
Methods: RT Safe cranial and thorax phantoms wi...

Dosimetric Characterization of Spatial Fractionation Collimator for Ultra-High Dose Rate Electron Beam

Authors: Lily Jo Bertemes, Careesa Billante, Ashley Cetnar, Arnab Chakravarti, Nilendu Gupta, Sagarika Jain, Maximilian Stephen Meineke, Allison N. Palmiero, Runhe Tan

Affiliation: The Ohio State University - James Cancer Hospital, Department of Radiation Oncology, The Ohio State University Wexner Medical Center, Department of Radiation Oncology, Ohio State University Comprehensive Cancer Center, The Ohio State University, The James Cancer Center

Abstract Preview: Purpose: Ultra-High Dose Rate Radiation Therapy (UHDR-RT) induces normal tissue sparing while maintaining iso-effective tumor control compared to conventional methods, known as the “FLASH effect”. How...

Dosimetric Characterization of Sun Nuclear EDGE Diodes in the Plateau Region of Proton Pencil Beam Scanning (PBS) Fields

Authors: Wesley S. Culberson, Ryan Gardner, Patrick M Hill, Mark Pankuch, Karsten K. Wake

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, University of Wisconsin, Northwestern Medicine Proton Center

Abstract Preview: Purpose: To assess the dosimetric capabilities of Sun Nuclear (Melbourne, FL) EDGE Diode Detectors™ for measurements in the plateau region of pencil beam scanning (PBS) fields. Many clinical dosimeter...

Dosimetric Comparison & Error Analysis of Aapm TG51 & WGTG51-e Protocol with Icru-90 Key-Data for High-Energy Clinical Electron Beam

Authors: Amar K. Basavatia, Sandeepan Ganguly, Lee C. Goddard, Wolfgang A. TomĂŠ

Affiliation: Montefiore Medical Center

Abstract Preview: Purpose: To investigate the dosimetric impact of WGTG51-e Report 385, recently updated CoP for clinical electron beams. This study uses a chamber specific effective point of measurement (EPOM) shift t...

Dosimetric Parameter Cross-Check Evaluations for Dedicated Biologically-Guided Radiotherapy Linac Using Two Water Phantom Systems

Authors: Nguyen Phuong Dang, Mason Hazlett, Lijun Ma, Yutaka Natsuaki, William T. Watkins, Zhengzheng Xu, Timothy Pok Chi Yeung

Affiliation: Reflexion Medical Inc,, Radiation Oncology, Keck School of Medicine of USC, RefleXion Medical, Department of Radiation Oncology, City of Hope National Medical Center

Abstract Preview: Purpose: This is the first study reporting the beam dosimetric parameter cross-checks of Reflexion linac using different water phantom systems and detectors. The difference in measurements using diffe...

Dosimetry Commissioning of a Commercial Cabinet X-Ray Irradiator for Small Animal Irradiation

Authors: Sang Hyun Cho, Amrit Kaphle, Sunil Krishnan, Neerajan Nepal

Affiliation: The University of Texas MD Anderson Cancer Center, The University of Texas Health Science Center

Abstract Preview: Purpose: To determine the basic dosimetry parameters and characteristics of a commercial cabinet x-ray unit for small animal irradiation as well as the specific dosimetry parameters for concurrent irr...

Effects of Enhanced Leaf Modeling on Single-Isocenter Multi-Target Stereotactic Radiosurgery Dose Accuracy

Authors: Thomas R. Mazur, Kevin Renick, Matthew C. Schmidt, Xiaodong Neo Zhao

Affiliation: Washington University in St. Louis School of Medicine, Washington University School of Medicine

Abstract Preview: Purpose: To compare dose calculation accuracy for single-isocenter multi-target stereotactic radiosurgery plans (SIMT-SRS) in Eclipse V18.0 with enhanced leaf model (ELM) using the anisotropic analyti...

Evaluating Pulse Normalization for Enhanced Ion Chamber Signal Correction in Relative Dosimetry during Beam Scanning

Authors: Alejandro Cuadra, Paulina E. Galavis, Juan Leal, Enrique Lozano, Franklin Reggio, Gabriel Zelada

Affiliation: ClĂ­nica Iram, Clinica Alemana, Hospital ClĂ­nico de Magallanes, E&G Medical Systems Ltda, NYU Langone Health

Abstract Preview: Purpose: To investigate and compare the new method “Pulse Normalization” proposed by Sun Nuclear to correct ion chamber signal for fluctuations in the accelerator output while performing relative dosi...

Evaluating the Impact of Beam Spot Spacing on Dose Rates and Field Uniformity for Small Animal Proton Ultra-High Dose Rate Irradiation

Authors: Jack Biondo, Audrey Magness, Anthony E. Mascia, Zhiyan Xiao, Yongbin Zhang

Affiliation: Cincinnati Children's Proton Therapy Center

Abstract Preview: Purpose: Proton FLASH-RT has shown promise reducing normal tissue toxicity while maintaining tumor control. However, in vivo experiments critically depend on achieving ultra-high dose rate (UHDR) and ...

Evaluation of Charge Collection Performance in the A30 Prototype Parallel Plate Ion Chamber in Ultra-High Dose Rate Beam

Authors: Mervat A. Alharbi, Wesley S. Culberson

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison, Medical Physics Department, School of medicine and Public Health, University of Wisconsin-Madison

Abstract Preview: Purpose: The charge collection using ionization chambers is challenging at ultra-high dose rates (UHDR) due to the high ion recombination The Exradin A30 prototype parallel-plate ion chamber manufactu...

Evaluation of Ion Chamber Performance and Suitability for Flash Proton Therapy Dosimetry

Authors: Seohyeon An, Yoonsun Chung, Seonghoon Jeong, Seongmoon Jung, Chae-Eon Kim, In Jung Kim, Sung Hun Kim, Se Byeong Lee, Sang-il Pak, Jong In Park

Affiliation: POHANG ACCELERATOR LABORATORY, Hanyang University, Korea Research Institute of Standards and Science (KRISS), Ilsan Paik Hospital, National Cancer Center, National Cancer Center Korea, Korea Research Institute of Standards and Science

Abstract Preview: Purpose: To evaluate the performance of three ion chambers—Advanced Markus (AMC), PinPoint, and Roos—under FLASH proton beam conditions and assess the response of the nozzle monitor chamber for their ...

Evaluation of the Improvements of a New Leaf Model (Enhanced Leaf Model) for the Halcyon

Authors: Evan Barber, Gloria P. Beyer, Callum Hartley, Jordi Saez, Philip Wheeler

Affiliation: Department of Radiation Oncology, Hospital Clinic de Barcelona, Department of Radiotherapy Physics, Velindre University NHS Trust, Medical Physics Services, LLC

Abstract Preview: Purpose: To evaluate the Enhanced Leaf Model (ELM) in Eclipse v18 to the standard leaf model for the Halcyon multileaf collimator (MLC) using a measurement-based method.
Methods: The Halcyon’s doub...

Feasibility of Using 68ga-PSMA for Biology-Guided Radiotherapy (BgRT) Treatment

Authors: Girish Bal, Thomas I. Banks, Bin Cai, Neil Desai, Aurelie Garant, Orhan Oz, Elizeva Phillips, Rameshwar Prasad, Chenyang Shen, Robert Timmerman

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical

Abstract Preview: Purpose: This study reports findings from the first-in-human imaging-only trial evaluating the feasibility of using the novel PET tracer 68Ga-PSMA-11 (Illuccix) to guide external beam radiotherapy on ...

First Phantom Testing of Biology-Guided Radiotherapy for Sequential Integrated Boost Radiotherapy

Authors: Girish Bal, David J. Carlson, Huixiao Chen, Zhe (Jay) Chen, Emily A. Draeger, Dae Yup Han, Henry S. Park

Affiliation: RefleXion Medical, Department of Therapeutic Radiology, Yale University School of Medicine

Abstract Preview: Purpose: This study explores the feasibility, accuracy, and dosimetric performance of hybrid biology-guided radiotherapy (BgRT) combined with image-guided radiotherapy (IGRT) for delivering sequential...

Hyperbaric Oxygen Therapy Prior to SRS Does Not Enhance Radiosensitivity in the Murine Glioblastoma Model

Authors: Beverly Allen, Jay C. Buckey, David J. Gladstone, P. Jack Hoopes, David I Hunter, Armin Tavakkoli

Affiliation: Thayer School of Engineering, Dartmouth College, Geisel School of Medicine, Dartmouth College, Geisel School of Medicine, Thayer School of Engineering

Abstract Preview: Purpose: Hyperbaric oxygen (HBO) therapy immediately prior to radiation therapy has been proposed as treatment to enhance radiosensitivity of hypoxic tumors. A murine glioblastoma model was utilized t...

Impact of Ion Chamber Selection on Enhanced Leaf Modeling Predictions of Dosimetric Leaf Gap and Leaf Transmission Factors

Authors: Michael Ashenafi, Nicholas Becerra Espinosa, Mario Ramos Gallardo, Matthew Pacella, Sean M. Tanny

Affiliation: Department of Radiation Oncology, University of Rochester

Abstract Preview: Purpose: A new multileaf collimator (MLC) model has been introduced in Varian Eclipse v18.0, with the treatment planning system (TPS) explicitly modeling the leaf end effects. The vendor recommends a ...

Initial Comparison of 3D CBCT Performance: New Mobile C-Arm Vs. O-Arm Unit

Authors: Wendy Siman, Wei Zhou

Affiliation: University of Colorado Anschutz Medical Campus, School of Medicine

Abstract Preview: Purpose:
To compare the image quality and radiation dose of 3D cone-beam CT modes of a mobile C-arm and an O-arm unit for intraoperative imaging.
Methods:
A 50-Âľm tungsten wire was imaged at ...

Inter-System and Inter-Layer Dlg Variations in Halcyon/Ethos Mlcs: Implications for Dosimetric Matching and User-Adjustable TPS Models

Authors: Evan Barber, Gloria P. Beyer, Matthew J. Daniels, Callum Hartley, Jordi Saez, Philip Wheeler

Affiliation: TrueNorth Medical Physics, Department of Radiotherapy Physics, Velindre University NHS Trust, Department of Radiation Oncology, Hospital Clinic de Barcelona, Medical Physics Services, LLC

Abstract Preview: Purpose: To quantify inter-system and inter-layer dosimetric leaf gap (DLG) variations in Halcyon/Ethos multileaf collimators (MLCs) using custom sweeping gap tests, and to evaluate implications for c...

Ir-192 Percentage Depth Ionization of PLA and Ballistic Gelatin Compared to Water

Authors: ChangSeon Kim, Andrew Lukban, Mario Serrano-Sosa, Ching-Ling Teng, Nadia M. Vassell

Affiliation: Northwell, Mount Sinai Beth Israel

Abstract Preview: Purpose:
The flexible nature of ballistic gelatin and 3D printed material such as PLA lend themselves to phantom studies in brachytherapy. While these materials can allow for easy simulation of cat...

Management of 4D CBCT Dose for Patients with Implanted Cardiac Devices

Authors: Won Chang, Vadim L. Stakhursky, Yevgeniy Vinogradskiy

Affiliation: Jefferson Einstein, Alliance Cancer Specialists, Thomas Jefferson University

Abstract Preview: Purpose: 4DCBCT is a powerful tool for localization of moving targets when treating lung tumors with hypofractionated regimens (SBRT). However, for patients with implanted cardiac devices (ICD) in clo...

Mobetron Quality Assurance Tools

Authors: Robert A. Dahl

Affiliation: Mayo Foundation

Abstract Preview: Purpose: To develop tools to simplify/accelerate the quality assurance testing of the Mobetron mobile linear accelerator and increase safety when moving it to different OR’s.

Methods: The Mobet...

Monitor Unit (MU) Substructure Analysis for Low MU Deliveries

Authors: Indra J. Das, Ahtesham U. Khan, Andrew J. White, Poonam Yadav

Affiliation: Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine

Abstract Preview: Purpose: During intensity modulated radiotherapy (IMRT) planning, low MU segments (< 3 MU) are commonly avoided due to documented dosimetric nonlinearity and poor reproducibility. This work aims to ex...

Monte Carlo Derived Correction Factors for Ion Chambers Used in the Calibration of Gamma Knife Perfexion Model: Impact of Phantom Materials and Chamber Orientation on Dosimetric Accuracy

Authors: Catherine Coolens, Robert K. Heaton, Lalageh Mirzakhanian, Tasnim Rahman, Jan P. Seuntjens

Affiliation: Princess Margaret Cancer Centre & University of Toronto, McGill University, Princess Margaret Cancer Centre, Princess Margaret Hospital, University of Toronto

Abstract Preview: Purpose: Commissioning of a Gamma KnifeÂŽ (GK) (Elekta, Sweden) unit requires precise dosimetric reference measurements, particularly for small fields. The IAEA TRS-483/AAPM TG-155 code of practice (20...

On the Sensitivity Evaluation of End-to-End Test in Radiotherapy

Authors: Yussuf A. Abdelal, Sebastien A. Gros, Luke Layman, Anil Sethi

Affiliation: Stritch School of Medicine, Cardinal Bernardin Cancer Center, Loyola University Chicago, Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago

Abstract Preview: Purpose:
End-to-end (E2E) test is a vital QA check of the overall radiotherapy process from simulation imaging to treatment delivery. Although clinical passing criteria are available, guidelines on...

Optimized Methodology for Accurate Half-Value Layer Measurement in Preclinical X-Ray Cabinet Systems

Authors: Paolo Pellicioli, Mohammad Rezaee, Ehsan Tajikmansoury, John W. Wong

Affiliation: Institute of Anatomy, University of Bern, Baltzerstrasse, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine

Abstract Preview: Purpose: Half-value layer (HVL) is a critical parameter for commissioning and quality assurance of preclinical x-ray irradiators. However, measuring HVL in cabinet systems presents challenges due to s...

Optimizing Low-Dose Imaging Parameters for Dual-Energy Cone-Beam Computed Tomography in Image-Guided Radiation Therapy

Authors: Sebastien A. Gros, Hyejoo Kang, Andrew Keeler, Luke Layman, Jason Patrick Luce, Ha Nguyen, John C. Roeske

Affiliation: Department of Radiation Oncology, Stritch School of Medicine, Loyola University Chicago, Stritch School of Medicine Loyola University Chicago, Cardinal Bernardin Cancer Center, Loyola University Chicago

Abstract Preview: Purpose:
This study aims to optimize virtual monoenergetic (VM) images obtained from dual-energy (DE) cone-beam computer tomography (CBCT) protocols for Image-Guided Radiation Therapy (IGRT). The o...

Preclinical Dosimetric Evaluation for Small Animal Study to Investigate Normal Tissue-Sparing Effects in the Electron Ultra-High Dose-Rate (FLASH) Environment

Authors: Ashok Bhandari, Andrew Joseph Fanning, Kyle J. Gallagher, Brendan Graff, Christopher Jenkins, Kyuhak Oh, Ying Yan, Su-Min Zhou

Affiliation: University of Nebraska Medical Center

Abstract Preview: Purpose: This study aimed to design a robust experimental setup to ensure accurate dose delivery using ultra-high-dose-rate for small animal experiments by conducting dosimetric evaluations prior to a...

Radiation Shielding Considerations for Ultra-High Dose Rate Electron Flash Radiation Therapy

Authors: Alexandru Badalan, Peter Petric, I. Antoniu Popescu, Andrew Kyle Henderson Robertson

Affiliation: Bc Cancer, BC Cancer - Vancouver, BC Cancer

Abstract Preview: Purpose: Ultra-high dose rate (>40 Gy/s) or “FLASH” radiation therapy (RT) has the potential to improve cancer treatment through reduced radiation side effects. While electron FLASH beams can be produ...

Rapid 3D Prototyped Solid-Source Phantoms for Quality Assurance of Biology-Guided Radiotherapy (BgRT)

Authors: Jon Burns, Andrew Groll, Gopinath Kuduvalli, Thomas Laurence, Manoj Narayanan, Jeffrey Schmall, Sanchit Sharma

Affiliation: RefleXion Medical

Abstract Preview: Purpose: To simplify BgRT testing we have developed techniques that use 3D resin printed structures that can be filled with Ge-68 epoxy. This approach allows the development of highly complex, clinica...

Reduction of the Charge Build-up Effect on the Beam Current Transformers for Real-Time Monitoring of Ultra-High Dose per-Pulse Electron Beams

Authors: Wesley S. Culberson, Miguel Angel Flores Mancera, Jeff Radtke

Affiliation: Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin - Madison

Abstract Preview: Purpose: Beam current transformers (BCTs) are a promising alternative to ion chambers for real-time monitoring of ultra-high dose per-pulse (UHDPP) beams. The signal of the BCT is insensitive to ion r...

Relative Optimized Linearization for Film Dosimetry with Non-Uniformity Correction

Authors: Piotr Pater, Nicholas G. Zacharopoulos

Affiliation: McGill University, Medical Physics Unit, Gerald Bronfman Department of Oncology, McGill University

Abstract Preview: Purpose: To develop a method for accurate relative film dosimetry that incorporates non-uniformity
corrections.
Methods: The accuracy of Devic’s [1] linearization approach was evaluated using si...

Small Fields Output Factor Measurements in 1.5 MR-Linac

Authors: Thomas I. Banks, Tsuicheng D. Chiu, Viktor M. Iakovenko, Christopher Kabat, Chang-Shiun Lin, Mu-Han Lin, Arnold Pompos

Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX

Abstract Preview: Purpose: The superior soft-tissue contrast provided by MR imaging offers favorable conditions for the effective application of stereotactic body radiation therapy (SBRT). Accurate small field dosimetr...

Streamlined Calibration of Mosfet Dosimeters for Radixact Systems: Addressing Angular Dependence and Beam Profile Challenges

Authors: Guang-Pei Chen, Renae Conlin, Juan A. Garcia-Alvarez, Kirk Morris, Haidy G. Nasief, Eenas A. Omari, Eric S. Paulson

Affiliation: Department of Radiation Oncology, Medical College of Wisconsin

Abstract Preview: Purpose: Cumulative dose limits make replacing and calibrating Metal Oxide Semiconductor Field Effect dosimeters (MOSFET-d) used for in-vivo dosimetry a common clinical task. Calibration protocols for...

Streamlining Orthovoltage QA: Feasibility of IC Profiler Dosimetry and Workflow Optimization

Authors: Huixiao Chen, Zhe (Jay) Chen, MinYoung Lee, Sameer Taneja

Affiliation: Yale School of Medicine, Department of Therapeutic Radiology, Yale University School of Medicine

Abstract Preview: Purpose: Superficial radiation therapy uses low-energy x-rays to treat various types of cancers, including non-melanoma skin cancers, and dermatological conditions such as keloid scars, mycosis fungoi...

The Use of a Milled NIST Traceable Tld for End-to-End Validation in Mlc and Cone SRS Programs.

Authors: Ross Bland, Zachary A. Christ, Sophy Mangana, Feba Mathew, Stephanie K. Phoenix, Joseph Salloum, Jason D. Stanford, William Zollinger

Affiliation: Forrest General Cancer Center, Northeast Louisiana Cancer Institute, Florida Atlantic University

Abstract Preview: Purpose: The objective of this paper is twofold: 1) to explore the efficacy of using referenced beam models supplied by the vendor (Brainlab) and 2) the efficacy of NIST traceable TLD for end-to-end v...

Towards Arbitrary Phantom Patient Specific IMRT QA on Reflexion X1

Authors: Andrew Groll, Ayan Mitra, PhD, Manoj Narayanan, Sanchit Sharma, Ray Yang, Timothy Pok Chi Yeung

Affiliation: Reflexion Medical Inc,, RefleXion Medical

Abstract Preview: Purpose: To develop a versatile QA tool enabling dose recalculation of a patient’s plan sinogram redeployed onto arbitrary replacement phantom geometry, and extract computed dose along detector planes...

Treatment Dose Reconstruction of Digitized Deliveries on Reflexion X1 System Based on Megavoltage Imager and Dose Monitor Chamber

Authors: Angela J Da Silva, Andrew Groll, Gopinath Kuduvalli, Thomas Laurence, David W. Meer, Manoj Narayanan, Mingshan Sun, Don Vernekohl, Ray Yang

Affiliation: RefleXion Medical

Abstract Preview: Purpose: To implement post-treatment review of delivered dose fractions on RefleXion X1 accounting for independent detection of transmitted beamlets and transient dose fluctuations of individual pulse...

Treatment Planning System Modelling of a New Commercial Rotational Table

Authors: Michael Armstrong, Courtney R. Buckey, Quan Chen, Suzanne J. Chungbin, Mirek Fatyga, Yi Rong, Jun Tan, Xiang Sheng Yan

Affiliation: Mayo Clinic Arizona, Mayo Clinic

Abstract Preview: Purpose: To model a commercial rotational table in treatment planning system (TPS) for accurate dose optimization and calculation.

Methods: A commercial rotational table (CDR EquilibriumÂŽ) is r...

Voxel-Based Micro-Yucatan Minipig Phantoms for Use in Internal Dosimetry

Authors: John P. Aris, Wesley E. Bolch, Natalia Estefania Carrasco-Rojas, Ann M. Chan, Chansoo Choi, Aitor Gallastegui Menoyo, Rowan James Milner, Bangho Shin, Maria M. Von Chamier

Affiliation: University of Florida

Abstract Preview: Purpose: In preclinical studies, minipigs serve as valuable experimental models for predicting absorbed doses due to their anatomical and physiological similarities to humans. However, minipig computa...