Authors: Steven DiBiase, Gurtej S. Gill, Haohua Billy Huang, Nicholas J. Lavini, Luxshan Shanmugarajah, Salar Souri, Samantha Wong
Affiliation: Stony Brook University, Northwell Health, Cornell University, NewYork-Presbyterian, New York-Presbyterian
Abstract Preview: Purpose: Clinical applications of deep learning-based algorithms have come to the radiation oncology field as organ at risk (OAR) auto contouring programs. We evaluated two of these algorithms’ (Radfo...
Authors: Theodore Higgins Arsenault, Kenneth W. Gregg, Beatriz Guevara, Lauren E Henke, Angela Jia, Rojano Kashani, Kyle O'Carroll, Alex T. Price, Adithya Reddy, Atefeh Rezaei, Daniel E Spratt, Runyon C. Woods
Affiliation: University Hospitals Seidman Cancer Center
Abstract Preview: Purpose: To evaluate the effect of unedited AI-generated contours used for online adaptive radiotherapy (FLOW-ART) on the plan quality of prostate treatments as compared to non-adaptive (non-ART) proc...
Authors: Jamie s Baker, Sam Beddar, Mahsa Dehghanpour, Ariel MT Hoang, Emma Holliday, Rachael M. Martin Paulpeter, Joshua S. Niedzielski, Luis Augusto Perles, Josie S Ruzek, Gabriel O. Sawakuchi
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, niversity of Texas MD Anderson Cancer Center School of Health Professions, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, University of Texas MD Anderson Cancer Center School of Health Professions
Abstract Preview: Purpose: This study aims to evaluate the dosimetric impact on organs at risk (OAR) of small versus large spot sizes when treating pelvic cancer patients with pencil beam scanning (PBS) proton therapy....
Authors: Mubasheer Chombakkadath, Tara E. Tyson, Iris Z. Wang
Affiliation: Roswell Park Comprehensive Cancer Center, University at Buffalo (SUNY)
Abstract Preview: Purpose: Deformable image registration (DIR) is critical in adaptive radiation therapy (ART). Existing DIR phantoms either simulate tumor shape or volume changes but lack comprehensive motion simulati...
Authors: Arpit M. Chhabra, J Isabelle Choi, Minglei Kang, Haibo Lin, Hang Qi, Charles B. Simone, Shouyi Wei, Irini Yacoub, Francis Yu, Xingyi Zhao, Ajay Zheng
Affiliation: New York Proton Center, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose:
Pencil beam scanning (PBS) proton therapy effectively treats ocular cancer by minimizing exit doses to normal tissues. However, challenges remain in sparing nearby organs-at-risk(OARs). Ul...
Authors: Shifeng Chen, Mariana Guerrero, Brian A. Hrycushko, Kai Huang, Kai Jiang, Narottam Lamichhane, Paul M. Medin, Elizabeth Nichols
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland School of Medicine, Department of Radiation Oncology, University of Maryland Medical Center
Abstract Preview: Purpose: Unloaded needle catheters, if not handled properly, pose a risk for channel misconnection in interstitial high dose rate (iHDR) brachytherapy. This study aims to investigate the dosimetric im...
Authors: Gabriel Lucas Andrade de Sousa, Einsley-Marie Janowski, Cam Nguyen, Krishni Wijesooriya
Affiliation: Department of Radiation Oncology, University of Virginia, Department of Physics, University of Virginia
Abstract Preview: Purpose: Optimizing radiation therapy (RT) to spare the immune system may improve Overall Survival (OS) in cancer patients. This study develops a computational algorithm to identify optimal dose-volum...
Authors: Ramesh Boggula, Lincoln Houghton
Affiliation: Karmanos Cancer Institute, Wayne State University
Abstract Preview: Purpose: To evaluate an approach that selectively applies adaptive re-planning only when needed to reduce clinical workload while maintaining treatment quality. Daily adaptive radiotherapy (ART) has t...
Authors: Liqin HU, Tao He, Jing JIA, Pengcheng LONG, Wei Meng, Yang Yuan
Affiliation: SuperAccuracy Science & Technology Co. Ltd.
Abstract Preview: Purpose: A multi-criteria optimization method based on reinforcement learning and adaptive boosting(RLAB MCO) has been developed to enhance radiotherapy plan quality by offering reasonable and effecti...
Authors: Shari Damast, Svetlana Kuznetsova, Christopher J. Tien
Affiliation: Yale University School of Medicine, Department of Therapeutic Radiology, Yale University School of Medicine
Abstract Preview: Purpose: Current contour similarity evaluation approaches (Dice Similarity Coefficient, Mean Distance to Agreement) are limited to geometric agreement without assessment of ultimate dosimetric impact....
Authors: Christopher L. Deufel, Suman Gautam, William Y. Song
Affiliation: Virginia Commonwealth University, Mayo Clinic
Abstract Preview: Purpose: Direction modulated brachytherapy creates anisotropic dose distribution from an isotropic source. This study aims to develop a truncated conditional value at risk optimization algorithm for D...
Authors: Doris Dimitriadis/Dimitriadou, M. Saiful Huq, Ronald John Lalonde, Fang Li, Noor Mail, Adam Olson
Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, UPMC
Abstract Preview: Purpose: The objective of this study was to qualitatively evaluate Prostate Hypersight Cone-Beam CT (HSCBCT) images and assess its capability for Limbus auto-contouring. The qualitative evaluation and...
Authors: Leslie Bell, Kai Ding, Reza Farjam, Russell K Hales, Sarah Han-Oh, Hamed Hooshangnejad, Jina Lee, K. Ranh Voong
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Johns Hopkins University
Abstract Preview: Purpose: Optimal beam arrangement is crucial in automation and standardization of thorax radiotherapy where substantial tissue heterogeneity and several critical organs at risks (OARs) exist. Here, we...
Authors: Rani Anne', Wenchao Cao, Yingxuan Chen, Wookjin Choi, Firas Mourtada, Yevgeniy Vinogradskiy
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose: In-room mobile cone-beam CT (CBCT) is emerging to enhance high-dose-rate (HDR) brachytherapy workflow using on-demand imaging. However, metal artifacts from X-ray markers inside gynecological...
Authors: Asma Amjad, Renae Conlin, Beth A. Erickson, William Hall, Eric S. Paulson, Christina M. Sarosiek
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: The adapt-to-shape (ATS) workflow on the MR-Linac involves manual contour edits followed by treatment plan reoptimization on daily pre-beam MRIs. A verification image is acquired after plan o...
Authors: Indrin J. Chetty, Jing Cui, Mitchell Kamrava, Tiffany M. Phillips, Jennifer M. Steers, Brad Stiehl
Affiliation: Department of Radiation Oncology,Cedars-Sinai Medical Center, Cedars-Sinai Medical Center
Abstract Preview: Purpose: Auto-contouring for HDR interstitial brachytherapy can be confounded by large deformation in anatomy and image quality. Here we evaluated the performance of an AI-based auto-contouring softwa...
Authors: Pradeep Bhetwal, Wookjin Choi, Adam Dicker, Rupesh Ghimire, Yingcui Jia, Lauren Nkwonta, Yevgeniy Vinogradskiy, Wentao Wang, Maria Werner-Wasik
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose: Multi-disciplinary clinics are becoming standard of care for patients with lung cancer treated with SBRT. To improve clinical decision support in a multi-disciplinary clinic, it would be bene...
Authors: Deepak Agrawal, Subhash Gupta, Shashanksharad Kale, Gopishankar Natanasabapathi, Manoj Phalak, Dhanabalan Rajasekaran, Surendra Kumar Saini, Subramani Vellaiyan
Affiliation: All India Institute of Medical Sciences (AIIMS), All India Institute of Medical Sciences
Abstract Preview: Purpose:
To evaluate planning strategy for uveal melanoma tumor (UM) in gamma knife stereotactic radiosurgery (GKSRS) using Lightning inverse planning software for treatment planning.
Methods:
Authors: Silambarasan Anbumani, Nicolette O'Connell, Eenas A. Omari, Amanda Pan, Eric S. Paulson, Lindsay Puckett, Monica E. Shukla, Dan Thill, Jiaofeng Xu
Affiliation: Elekta Inc, Elekta Limited, Linac House, Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Accurate electron density information from on-board imaging is essential for direct dose calculations in adaptive radiotherapy (ART). This study evaluates a deep learning model for thoracic s...
Authors: Wenhua Cao, Hadis Moazami Goudarzi, Madison Emily Grayson, Zongsheng Hu, Gino Lim, Steven Hsesheng Lin, Radhe Mohan
Affiliation: The University of Texas MD Anderson Cancer Center, Department of Industrial Engineering, University of Houston, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Proton Arc Therapy (PAT) offers significant potential in treating complex cancer cases by delivering a continuous radiation dose as the gantry rotates. This study aims to investigate the pote...
Authors: Steve B. Jiang, Dan Nguyen, Chenyang Shen, Fan-Chi F. Su, Jiacheng Xie, Shunyu Yan, Daniel Yang, Ying Zhang, You Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Laboratory, Department of Radiation Oncology, UT Southwestern Medical Center, The University of Texas at Dallas
Abstract Preview: Purpose: Accurate delineation of treatment targets and organs-at-risk is crucial for radiotherapy. Despite significant progress in artificial intelligence (AI)-based automatic segmentation tools, effi...
Authors: Mylinh Dang, Laila A Gharzai, Xinlei Mi, Poonam Yadav
Affiliation: Northwestern Feinberg School of Medicine, Northwestern Memorial Hospital, Northwestern University Feinberg School of Medicine, Northwestern Medicine
Abstract Preview: Purpose: Delineation of organs at risk (OAR) in the head/neck region requires substantial physician time. Many artificial intelligence (AI) based auto-contouring software are commercially available. T...
Authors: Awens Alphonse, Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Samuel Richter, Lauren A. Rigsby, Tino Romaguera, Hina Saeed, Nishan Shrestha, Somol Sunny
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: This study evaluates the necessity and potential benefits of online adaptive stereotactic body radiotherapy (SBRT) for prostate cancer using the ViewRay MR-Linac system. By leveraging real-ti...
Authors: Hao-Wen Cheng, Jonathan G. Li, Chihray Liu, Wen-Chih Tseng, Guanghua Yan
Affiliation: University of Florida
Abstract Preview: Purpose: This study develops and evaluates deep learning (DL) models for predicting 3D dose distributions in simultaneous integrated boost (SIB) prostate cancer treatment using the Elekta Unity MR-Lin...
Authors: Sven Ferguson, S. Murty Goddu, Ana Heermann, Taeho Kim, Nels C. Knutson, Hugh HC Lee, Shanti Marasini, Timothy Mitchell, Seungjong Oh, Kevin Renick
Affiliation: Washington University in St. Louis School of Medicine, Washington University School of Medicine in St. Louis, Department of Radiation Oncology, Washington University School of Medicine in St. Louis
Abstract Preview: Purpose: In the Gamma Knife stereotactic radiosurgery (GK-SRS), the delineation of organs-at-risks (OARs) was not fully automated. Due to the cumbersome nature of manual OAR contouring, dose evaluatio...
Authors: Jon Hansen
Affiliation: Washington University in St Louis
Abstract Preview: Purpose: Commercially available auto-segmentation software was utilized to generate institution-specific optimization structures for spine stereotactic body radiation therapy (SBRT). Implementation of...
Authors: Matthew J Ferris, Jason K Molitoris
Affiliation: Department of Radiation Oncology, University of Maryland School of Medicine, University of Maryland
Abstract Preview: Purpose: Anatomy changes often happen in head-and-neck (HN) patients treated with proton radiation therapy. These changes can result in deteriorations of target dose coverage and increased dose to org...
Authors: Katja M. Langen, William Andrew LePain, Robert Muiruri, Vivi Nguyen, Mosa Pasha, Roelf L. Slopsema, Alexander Stanforth, Yinan Wang, Mingyao Zhu
Affiliation: Emory Healthcare, Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Intensity modulated proton therapy (IMPT) treatment planning for craniospinal irradiation (CSI) is complex and requires extensive effort from the planner. This study aims to enhance planning ...
Authors: Shane McCarthy, Damodar Pokhrel, William St. Clair, Eddy S Yang
Affiliation: University of Kentucky, Department of Radiation Medicine
Abstract Preview: Purpose: Demonstration of automated stereotactic treatment planning for recurrent head and neck (RHN) cancers using knowledge-based planning, multicriteria optimization (MCO), and dosimetric scorecard...
Authors: Laurence Edward Court, Raphael Douglas, David Fuentes, Anuja Jhingran, Barbara Marquez, Raymond Mumme, Christine Peterson, Julianne M. Pollard-Larkin, Surendra Prajapati, Dong Joo Rhee, Thomas J. Whitaker
Affiliation: MD Anderson Cancer Center, The University of Texas MD Anderson Cancer Center, MD Anderson, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center
Abstract Preview: Purpose: Safe deployment of auto-contouring models requires the inclusion of automated quality assurance (QA). One approach is to use an independent auto-contouring model and compare the contours geom...
Authors: Rex A. Cardan, Carlos E. Cardenas, Quan Chen, Jingwei Duan, Joseph Harms, Joel A. Pogue, Richard A. Popple, Yi Rong, Dennis N. Stanley, Natalie N. Viscariello, Libing Zhu
Affiliation: Washington University in St. Louis, The University of Alabama at Birmingham, Mayo Clinic Arizona, University of Alabama at Birmingham
Abstract Preview: Purpose: Manual verification of organs-at-risk(OARs) delineations is a critical yet time-intensive process, often susceptible to unintentional oversights. To assist the reviewing process, a population...
Authors: Kristen A. Duke, Samer Jabor, Neil A. Kirby, Parker New, Niko Papanikolaou, Arkajyoti Roy, Yuqing Xia
Affiliation: St. Mary's University, The University of Texas San Antonio, UT Health San Antonio
Abstract Preview: Purpose:
The Segment Anything Model (SAM) is a foundational box-prompt-based model for natural image segmentation. However, its applicability to zero-shot 3D medical image segmentation, particularl...
Authors: Nebi Demez, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Umesh Rana, Nishan Shrestha, Somol Sunny
Affiliation: Florida Atlantic University, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: DynamicARC is an advanced proton therapy technique that leverages pencil beam scanning to deliver dose to the patient while the gantry rotates around the patient. This study investigates the ...
Authors: Sara Endo, Takeshi Fujisawa, Hidehiro Hojo, Masaki Nakamura, Hidenobu Tachibana
Affiliation: Department of Radiation Oncology, National Cancer Center Hospital East, Radiation Safety and Quality Assurance Division, National Cancer Center Hospital East
Abstract Preview: Purpose: To assess the clinical feasibility of deep learning (DL)-based automated contouring through qualitative and quantitative assessments.
Methods: Sixty cases were chosen, including 3 OARs...
Authors: Sam Armstrong, Jamison Louis Brooks, Nicole Johnson, Douglas John Moseley, Cassie Sonnicksen, Erik J. Tryggestad
Affiliation: Mayo Clinic
Abstract Preview: Purpose: To evaluate the feasibility of a shallow learning-based quality assurance (QA) tool designed to assist human reviewers in assessing organ-at-risk (OAR) contours for head and neck radiotherapy...
Authors: Haijian Chen, Katja M. Langen, William Andrew LePain, Claire Tran, Mingyao Zhu
Affiliation: Emory Healthcare, Emory University, Georgia Institute of Technology
Abstract Preview: Purpose: To validate the performance of a commercial deep-learning segmentation (DLS) tool for head and neck cancer (HNC) and thoracic and abdominal cancer (TAC) by comparing it to manual segmentation...
Authors: Aditya P. Apte, Joseph O. Deasy, Sharif F. Elguindi, Aditi Iyer, Jue Jiang, Eve Marie LoCastro, Jung Hun Oh, Amita Shukla-Dave, Harini Veeraraghavan
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: We present publicly shareable applications (apps) for AI-based radiotherapy segmentation workflows with pyCERR on Seven Bridges Cancer Genomics Cloud-based platform (CGC-SB)
Methods: Runni...
Authors: Raghavendiran Boopathy, Mansoor Khan, Srinidhi Rajagopalan
Affiliation: University of Oklahoma, University of Oklahoma Health Sciences Center
Abstract Preview: Purpose: This study aims to evaluate and compare the dosimetric outcomes of spatially fractionated radiotherapy (SFRT) grid planning techniques using Varian Eclipse for a Varian Edge C-arm LINAC syste...
Authors: Aditya P. Apte, Joseph O. Deasy, Jue Jiang, Nancy Lee, Sudharsan Madhavan, Nishant Nadkarni, Lopamudra Nayak, Harini Veeraraghavan, Wei Zhao
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: To track early response to radiotherapy using digital twins, it is crucial to quantify tumor volume and mass changes. Traditional tumor detection methods, particularly in image registration, ...
Authors: Michael Confer, Mark A. Newpower
Affiliation: University of Oklahoma Health Sciences Center
Abstract Preview: Purpose: A pediatric patient recently presented to our clinic for treatment for chordoma, which was near the brainstem. The clinician elected to treat this patient using intensity modulated proton the...
Authors: Tianyuan Dai, Xiaoying Fan, Shuting Wang, Yong Yin
Affiliation: Department of Graduate, Shandong First Medical University, Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences
Abstract Preview: Purpose: The purpose of this study was to investigate the interplay effect during intra-fractional motion and the effect of the robust optimization parameters for inter-fractional motion in the intens...
Authors: Benjamin Haibe-Kains, Ruiyan Ni, Alexandra Rink
Affiliation: Department of Medical Biophysics, University of Toronto, University Health Network
Abstract Preview: Purpose: Accurate auto-segmentation for targets and organs-at-risk (OARs) using deep learning reduces the delineating time in radiotherapy. In high-dose-rate brachytherapy, specific clinical criteria ...
Authors: Michael Burke, David J. Carlson, Yiu-Hsin Chang, Huixiao Chen, Zhe (Jay) Chen, Emily A. Draeger, Dae Yup Han, Vanessa Hill, Ann-Teresa Jasman, John Kim, Svetlana Kuznetsova, MinYoung Lee, Daniel Longo, Henry S. Park, Adam Shulman, Lauren Tressel, Weili Zhong
Affiliation: Department of Therapeutic Radiology, Yale University School of Medicine
Abstract Preview: Purpose:
The complexity of biology-guided radiotherapy (BgRT), particularly with systems like RefleXion X1, necessitates robust pre-treatment quality assurance (QA) to ensure patient safety, treatm...
Authors: Chase Cochran, Damodar Pokhrel, William St Clair
Affiliation: University of Kentucky, Department of Radiation Medicine, University of Kentucky, Radiation Medicine
Abstract Preview: Purpose: Currently, intraocular disease is primarily treated via COMS-plaques brachytherapy. Various stereotactic approaches via photons/proton beam have also been implemented (CyberKnife/GammaKnife/p...
Authors: Hao Gao, Yuting Lin, Jufri Setianegara, Aoxiang Wang, Peng Xiao, Qingguo Xie, Yanan Zhu
Affiliation: Department of Biomedical Engineering, Huazhong University of Science and Technology, Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Intensity-modulated proton therapy (IMPT) achieves uniform tumor dose distribution while sparing organs-at-risk (OAR) by optimizing spot weights across energy layers. Accelerating IMPT delive...
Authors: Parker Anderson, Elizabeth L. Bossart, Jonathan Cyriac, Nesrin Dogan, Robert Kaderka, Yihang Xu
Affiliation: University of Miami, University of Miami, Sylvester Comprehensive Cancer Center, University of Miami Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose:
Knowledge-based planning (KBP) can enhance the treatment planning process in cancer radiotherapy (RT). By training a KBP model with high-quality treatment plans developed by experts, dose-...
Authors: Ming Chao, Hao Guo, Tenzin Kunkyab, Yang Lei, Tian Liu, Kenneth Rosenzweig, Robert Samstein, James Tam, Junyi Xia, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose:
The aim of the study is to develop a trade-off prediction model to efficiently guide the treatment planning process for patients with stage III non-small cell lung cancer (NSCLC).
Metho...
Authors: Ming Chao, Hao Guo, Tenzin Kunkyab, Yang Lei, Tian Liu, Kenneth Rosenzweig, Robert Samstein, Junyi Xia, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose:
This study aims to develop and validate an Eclipse Scripting Application Programming Interface (ESAPI)-based planning toolbox that incorporates preset human expertise to improve planning e...
Authors: Michael Buckstein, Yang Lei, Tian Liu, Charlotte Elizabeth Read, Jing Wang, Kaida Yang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose: Inter-fraction anatomic variations in liver SBRT can cause significant discrepancies between planned and delivered doses. We developed a CBCT-based accumulative algorithm to directly compare ...
Authors: Yi Li
Affiliation: Department of Radiation Oncology, the First Affiliated Hospital of Xi'an Jiaotong University
Abstract Preview: Purpose: Advances in radiotherapy technology are crucial for improving cervical cancer (CC) treatment. This study explores a novel X-ray and γ-ray dual-modality radiation (TaiChiB) system, comparing i...
Authors: Alyssa Gadsby, William J. Godwin, Jennifer L. Harper, Daniel G. McDonald, Jean L. Peng, Alek K. Rapchak, Sean A Roles, Austin M. Skinner, Stephanie Tan
Affiliation: Medical University of South Carolina
Abstract Preview: Purpose: Multi-Criteria Optimization (MCO) theoretically allows for increased dose control during optimization. This study is the first to compare standard optimization (SO) and MCO for accelerated pa...
Authors: Aliasghar Rohani, Rui Zhang
Affiliation: Louisiana State University, Baton Rouge, Louisiana, Department of Radiation Oncology, Mary Bird Perkins Cancer Center
Abstract Preview: Purpose: This study aimed to evaluate the impact of simultaneous optimization of multi-photon beam energy and fluence on IMRT and VMAT treatment planning.
Methods: An Elekta linear accelerator (lin...
Authors: Adebayo Abe, Samuel Olaolu Adeneye, Bidemi I. Akinlade, Inioluwa Damilola Ariyo, Sylvester Entonu, Muhammad Habeebu, Adedayo O. Joseph, Oluwaseyi Oderinde, Oluwadara Ojediran, Margaret Dideolu Taiwo
Affiliation: University of Ibadan, University of Lagos, Missouri University of Science and Technology, Purdue University, NSIA-LUTH Cancer Center, University of Lagos, NSIA-LUTH Cancer Centre
Abstract Preview: Purpose:
Spatially Fractionated Radiation Therapy (SFRT) is an advanced radiotherapy technique designed to deliver highly heterogeneous radiation doses, aiming to optimize tumor control while minim...
Authors: Minbin Chen, Gang Liu, Manju Liu, Weiwei Sang, Pulin Sun, Mingyuan Ye, Fang-Fang Yin, Lihua Zhang, Haiming Zhu
Affiliation: Jiahui International Hospital, Radiation Oncology, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, The First People's Hospital of Kunshan
Abstract Preview: Purpose: This study aims to conduct a dosimetric comparison between lattice radiotherapy (LRT) and 3D grid treatment planning techniques, focusing on their differences in delivering three-dimensional ...
Authors: Awens Alphonse, Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Hina Saeed, Nishan Shrestha, Somol Sunny
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: Prostate stereotactic body radiation therapy (SBRT) requires precise dose delivery to the target volume and organ-at-risk (OAR) sparing. This study compares MR-Linac (MRL) and CyberKnife (CK)...
Authors: Awens Alphonse, Nebi Demez, Noufal Manthala Padannayil, Haley Park, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Nishan Shrestha, Somol Sunny
Affiliation: Florida Atlantic University, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: This study evaluates the dosimetric effects of patient positioning errors, including setup inaccuracies and yaw deviations, on dual-isocenter volumetric modulated arc therapy (VMAT) plans for...
Authors: Davide Brivio, Ivan M. Buzurovic, Thomas C. Harris, Desmond A. O'Farrell
Affiliation: Department of Radiation Oncology, Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Harvard Medical School, Brigham and Women's Hospital, Harvard Medial School, Dana-Farber Cancer Institute, Department of Radiation Oncology
Abstract Preview: Purpose: Cervical cancer can be treated with a brachytherapy boost following external beam radiotherapy. One applicator option is the Advanced Gynecological Applicator "Venezia" (Elekta) hybrid, consi...
Authors: Abby E. Besemer, Carolyn Eckrich, John M. Floberg, Michael J. Lawless, Jessica R. Miller, Joseph B. Schulz, Jordan M. Slagowski, Autumn E. Walter-Denzin
Affiliation: University of Wisconsin-Madison Department of Medical Physics, University of Wisconsin-Madison Department of Human Oncology, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology, Stanford University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: The aim of this treatment planning study was to evaluate the feasibility of escalating dose with HDR prostate brachytherapy to imaging-identified intraprostatic macroscopic lesions while mode...
Authors: Huisi Ai, Scott Glaser, Yi Lao, Percy Lee, Sara N. Lim, An Liu, Bo Liu, Borna Maraghechi, Kun Qing, Chengyu Shi, William T. Watkins, Terence Williams, Qiuyun Xu, Jiahua Zhu
Affiliation: WashU Medicine, Graduate Program in Bioengineering, University of California San Francisco-UC Berkeley, City of Hope Orange County, Department of Radiation Oncology, City of Hope National Medical Center, Department of Radiation Oncology, City of Hope Orange County, Department of Radiation Oncology, City of Hope Medical Center
Abstract Preview: Purpose: To employ a novel surface dose mapping approach for localized assessment of the dosimetric impact of Ethos adaptive radiotherapy (ART) for prostate cancer (PC).
Methods: This study include...
Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Shabbar Danish, Jing Feng, Wenzheng Feng, Joseph Hanley, Tingyu Wang
Affiliation: Hackensack Meridian Health, Jersey Shore University Medical Center
Abstract Preview: Purpose: ZAP-X is the newest cranial stereotactic radiosurgery (SRS) platform. Small-volume structures usually found in the head and neck may be susceptible to dose-volume averaging, which has not bee...
Authors: Min Su
Affiliation: Mount Sinai School of Medicine
Abstract Preview: Purpose: To evaluate dosimetric impact of target coverage and organ at risk (OARs) sparing for whole breast patient setup roll/yaw change in 3D-conformal radiotherapy.
Methods: 8 whole breast cases...
Authors: Darren Kaplan, Chenguang Liu, Mark Pankuch
Affiliation: Northwestern Medicine Proton Center
Abstract Preview: Purpose: This study evaluates the hypothesis that surface-guided radiation therapy for the breast or chest wall using proton PBS provides comparable target coverage and OARs sparing to x-ray-based IGR...
Authors: Yuzhen Ding, Hongying Feng, Jason Michael Holmes, Baoxin Li, Wei Liu, Daniel Ma, Lisa McGee, Samir H. Patel, Jean Claude M. Rwigema, Sujay A. Vora
Affiliation: Arizona State University, Department of Radiation Oncology, Mayo Clinic, Mayo Clinic Arizona, Mayo Clinic
Abstract Preview: Purpose:
Intensity-modulated proton therapy (IMPT) is a preferred treatment modality for head and neck (H&N) cancer patients, offering precise tumor targeting while sparing surrounding organs at ri...
Authors: Rita Buono, Elisabetta Cagni, Roberta Castriconi, Surendra Bahadur Chand, Marco Esposito, Claudio Fiorino, Valeria Landoni, Aldo Mazzilli, Eugenia Moretti, Lorenzo Placidi, Giulia Rambaldi Guidasci, Alessia Tudda
Affiliation: IRCCS San Raffaele Scientific Institute, Department of Advanced Technology, IRCCS Regina Elena National Cancer Institute, ASU FC Medical Physics, University Hospital of Parma AOUP, ICTP, B.P. Koirala Memorial Cancer Hospital, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Fatebenefratelli Isola Tiberina – Gemelli Isola
Abstract Preview: Purpose: To explore the feasibility and educational impact of transferring knowledge-based planning (KBP) models—developed using Italian breast radiotherapy data—to a Nepalese hospital, thereby demons...
Authors: Yang Lei, Tian Liu, Ren-Dih Sheu, Meysam Tavakoli, Jing Wang, Kaida Yang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Emory University
Abstract Preview: Purpose:
The study aimed to improve target and organ at risk (OAR) segmentation in low-dose-rate brachytherapy (LDR-BT) for prostate cancer treatment, by integrating clinical guidelines into deep l...
Authors: Chin-Cheng Chen, Chingyun Cheng, Longfei Diao, Benjamin Durkee, Minglei Kang, Haibo Lin, LeLe Liu, Yangguang Ma, Xuanqin Mou, YunTong Pei, Charles B. Simone, YuFei Wang, Xueqing Yan, Xingyi Zhao, Wang Zhengda
Affiliation: Peking University, St. Jude Children's Research Hospital, New York Proton Center, Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, School of Software Engineering, Xi’an Jiaotong University, School of information and communications engineering, Faculty of electronic and information engineering, Xi’an Jiaotong University, Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University School of Medicine, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: This study evaluates the effectiveness of apertures in improving lateral dose falloff in proton pencil beam scanning (PBS) single-energy Bragg peak (SEBP) FLASH radiotherapy (RT). The approac...
Authors: Robbie Beckert, Weiren Liu, Thomas R. Mazur, Allen Mo, Stephanie Perkins, Hailei Zhang, Tianyu Zhao
Affiliation: Washington University in St. Louis School of Medicine, University of South Florida, WashU Medicine
Abstract Preview: Purpose: Online adaptation may mitigate uncertainties in proton therapy arising from interfractional anatomical changes. While robust optimization accounts for setup and range uncertainties during pla...
Authors: Samira Dabaghmanesh, Beth A. Erickson, William Hall, Jason Hirshberg, An Tai
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose: Treatment plan evaluation for minimizing duodenal toxicity often involves multiple dose-volume constraints that vary based on fractionation. The Equivalent Uniform Dose (EUD) has emerged as a...
Authors: Gregory T. Armstrong, James E. Bates, Lei Dong, Ralph Ermoian, Jie Fu, Christine Hill-Kayser, Rebecca M. Howell, Sharareh Koufigar, John T. Lucas, Thomas E. Merchant, Tucker J. Netherton, Sogand Sadeghi
Affiliation: Department of Radiation Oncology, University of Washington and Fred Hutchinson Cancer Center, Department of Epidemiology and Cancer Control, St. Jude Children’s Research Hospital, St. Jude Children's Research Hospital, Department of Radiation Oncology, Fred Hutchinson Cancer Center, University of Washington, Department of Radiation Oncology, St. Jude Children’s Research Hospital, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Department of Radiation Oncology, University of Washington/ Fred Hutchinson Cancer Center, Department of Radiation Oncology, University of Pennsylvania, University of Pennsylvania, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: This study evaluates the adaptability and limitations of commercially available (MIM, RayStation) tools trained on predominately adult datasets (ages 20–60+ years) for delineating organs at r...
Authors: Christopher G. Ainsley, Pradeep Bhetwal, Yingxuan Chen, Wookjin Choi, Vimal K. Desai, Karen E. Mooney, Adam Mueller, Hamidreza Nourzadeh, Yevgeniy Vinogradskiy, Maria Werner-Wasik
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose: MR-guided adaptive radiotherapy (MRgART) has demonstrated improved outcomes for patients with pancreatic cancer. However, the time-consuming re-segmentation of targets and organs-at-risk (OAR...
Authors: Mark A. Newpower, Jill Taylor
Affiliation: University of Oklahoma Health Sciences Center
Abstract Preview: Purpose: RayStation 2024A allows planners to optimize intensity modulated proton therapy (IMPT) plans using discrete arcs which can then be converted to traditional pencil beam scanning (PBS) beams fo...
Authors: Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Umesh Rana, Hina Saeed, Nishan Shrestha, Somol Sunny
Affiliation: Florida Atlantic University, Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: DynamicARC is a novel pencil beam scanning (PBS) proton therapy technique with the potential to provide more conformal dose distributions and reduce treatment time. This study investigates th...
Authors: Yuchao Hu, Yajun Jia, Zhangmin Li, Yong Sang, Jianan Wu, Man Zhao
Affiliation: Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Department of Radiation Oncology, Guangzhou Concord Cancer Hospital, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital， Chinese Academy of Medical Sciences and Peking Union Medical College
Abstract Preview: Purpose: To evaluate the imaging dose of 4D-CBCT in patients treated with thoracic radiotherapy.
Methods: A model of the Elekta XVI imaging system was created in TOPAS software. Percentage depth do...
Authors: Chia-Lung Chien, Wen C. Hsi, Romy Megahed, Kayla Schneider
Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Department of Radiation Oncology, University of Arkansas for Medical Sciences
Abstract Preview: Purpose:
The dosimetric variations induced by inter-fractional anatomical changes in intensity-modulated proton therapy could impact the clinic outcomes for head-and-neck (HN) cancer patients. This...
Authors: Thomas I. Banks, Bin Cai, Andrew R. Godley, Yang Kyun Park, Hao Peng, Rameshwar Prasad, Chenyang Shen, Shunyu Yan, Haozhao Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, University of Texas Southwestern Medical Center
Abstract Preview: Purpose:
The RefleXion® X1 (RefleXion Medical, Inc., Hayward, CA) uniquely integrates KVCT and PET as on-board image guidance for radiotherapy. It has been installed and commissioned for clinical u...
Authors: Michelle Alonso-Basanta, Joshua Bryer, Lei Dong, Barbara Garcia, Elissa Khoudary, Brandon M. Koger, Taoran Li, Michael Salerno, Karen Tang, Boon-Keng Kevin Teo
Affiliation: University of Pennsylvania
Abstract Preview: Purpose: The Varian HyperSight imaging solution features a workflow for planning on CBCT images (CBCTp). This study evaluates the feasibility of CBCTp images in the setting of an offline adaptive plan...
Authors: Michael Evan Chaga, Timothy Chen, Darra M. Conti, Shabbar Danish, Jing Feng, Wenzheng Feng, Joseph Hanley, Tingyu Wang
Affiliation: Hackensack Meridian Health, Jersey Shore University Medical Center
Abstract Preview: Purpose: In August 2024, ZAP-X introduced automatic placement for isocenters in a DP-1010 upgrade for treatment planning. In this study, plans made by automatic placed isocenters are compared to those...
Authors: Adnan Jafar, Xun Jia, Michael B. Roumeliotis
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Johns Hopkins University
Abstract Preview: Purpose: HDR brachytherapy (HDRBT) treatment planning is challenging due to the need for high-quality plans under time pressure, considering anatomy and applicator geometry. This study proposes an exp...
Authors: Min Cheol Han, Hojin Kim, Jin Sung Kim, Hyejin Lee, Sac Lee, Yongdo Yun
Affiliation: Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine
Abstract Preview: Purpose: Carbon ion radiotherapy (CIRT) is characterized by high relative biological effectiveness (RBE), which must be integrated into the treatment planning process. This study aims to develop a nov...
Authors: Daniela Branco, John M Bryant, Surendra Bahadur Chand, Pratiksha Shahi, Joseph Weygand
Affiliation: Department of Radiation Oncology and Applied Science, Dartmouth Health, B.P. Koirala Memorial Cancer Hospital, , B.P Koirala Memorial Cancer Hospital, University of California San Diego / California Protons, Department of Radiation Oncology, Moffitt Cancer Center
Abstract Preview: Purpose:
Cervical cancer remains a significant health burden in Nepal, with 2169 new cases and 1313 deaths recorded in 2022. This study evaluates the feasibility of implementing step-and-shoot IMRT...
Authors: Girish Bal, Thomas I. Banks, Bin Cai, Neil Desai, Aurelie Garant, Orhan Oz, Elizeva Phillips, Rameshwar Prasad, Chenyang Shen, Robert Timmerman
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, University of Texas Southwestern Medical Center, UT Southwestern Medical Center, RefleXion Medical
Abstract Preview: Purpose: This study reports findings from the first-in-human imaging-only trial evaluating the feasibility of using the novel PET tracer 68Ga-PSMA-11 (Illuccix) to guide external beam radiotherapy on ...
Authors: Keisuke Fujii, Masahiro Kitagawa, Arezoo Modiri, Yuichiro Nakano, Ken N. Okada, Robabeh Rahimi, Akira SaiToh, Amit Sawant, Satoyuki Tsukano, Baoshe Zhang
Affiliation: University of Maryland, University of Maryland in Baltimore, Department of Computer and Information Sciences, Sojo University, Center for Quantum Information and Quantum Biology, Osaka University, Maryland University Baltimore, Department of Radiation Oncology, University of Maryland School of Medicine
Abstract Preview: Purpose: Fully personalized radiotherapy requires computational resources far exceeding those of conventional CPU/GPU systems. This study explores the use of quantum computing (QC) in radiotherapy pla...
Authors: Uriel Aura, Qing Chen, Arpit M. Chhabra, J Isabelle Choi, Chanda Guha, Meng Wei Ho, Sheng Huang, Minglei Kang, Stanislav Lazarev, Nancy Y Lee, Yang Lei, Haibo Lin, Hang Qi, Mahbubur Rahman, Charles B. Simone, Shouyi Wei, Irini Yacoub, Francis Yu, Anna Zhai, Ajay Zheng
Affiliation: DYN'R Medical System, New York Proton Center, Montefiore Medical Center and Albert Einstein College of Medicine, Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, Tianjin Medical University Cancer Institute&Hospital, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: Managing tumor motion during pencil beam scanning proton therapy remains challenging. This study investigated the feasibility and dosimetric benefits of Free-Breathing Respiratory-Gated Deliv...
Authors: Md. Yousuf Ali, Parvin Akhter Banu, Ehteshamul Hoque, Qazi Mushtaq Hussain, Md Jobairul Islam, Md. Abdul Mannan, Sadia Afrin Sarah, Mostafa Aziz Sumon, Ahammad Al Mamun Sweet, AFM Kamal Uddin
Affiliation: Labaid Cancer Hospital & Superspeciality Centre
Abstract Preview: Purpose: Radiotherapy for left-sided breast cancer can induce cardiac injury. Deep Inspiration Breath Hold (DIBH) is a technique that minimizes cardiac exposure during treatment. This study compares d...
Authors: Elizabeth L. Covington, Robert T. Dess, Charles S. Mayo, Michelle L. Mierzwa, Dan Polan, Jennifer Shah, Claire Zhang
Affiliation: University of Michigan, Department of Radiation Oncology, University of Michigan
Abstract Preview: Purpose: Auto-segmentation improves contour consistency and standardization in radiation therapy but may introduce variations from current practices, potentially impacting treatment outcomes and toxic...
Authors: Kenneth L. Homann, Natalie A Lockney, Hong Zhang
Affiliation: Department of Radiation Oncology, Vanderbilt University Medical Center, Vanderbilt University Medical Center
Abstract Preview: Purpose: The aim of this study is to develop a treatment planning methodology utilizing liver functional imaging via contrast-enhanced Magnetic Resonance Imaging (MRI) in patients undergoing stereotac...
Authors: Peng Dong, Elizabeth Kidd, Sheng Liu, Thomas R. Niedermayr, Oscar Pastor-Serrano, Lei Xing, Yong Yang, James Zou
Affiliation: Department of Biomedical Data Science, Stanford University, Department of Radiation Oncology, Stanford University, Stanford University
Abstract Preview: Purpose: Radiotherapy treatment planning is a time-consuming and potentially subjective process that requires iterative adjustments of optimization parameters to balance conflicting objectives. In thi...
Authors: Varsha Jain, Jun Kang, Paul Sulivan, Kate E. Verma, Yevgeniy Vinogradskiy
Affiliation: Thomas Jefferson University
Abstract Preview: Purpose:
Patients undergoing treatment for head and neck(H&N) cancers experience significant body contour changes throughout treatment. Body contour changes are due to tumor shrinkage, weight loss,...
Authors: Adnan Jafar, Xun Jia, An Qin
Affiliation: Johns Hopkins University
Abstract Preview: Purpose: 3D whole-brain radiotherapy (WBRT) is widely used due to its simplicity and effectiveness. While modern treatment planning systems, like RayStation, offer automated Field-in-Field planning, p...
Authors: Cheryl Anderson, Lara Best, Amanda Cherpak, Jennifer DeGiobbi, Marc C. LeBlanc, R. Lee MacDonald, Peter R. Martin, Natasha McMaster, Murali Rajaraman, James L. Robar, Lucy Ward, Derek Wilke, Kenny Zhan
Affiliation: Department of Radiation Oncology, QE2 Cancer Centre, Nova Scotia Health
Abstract Preview: Purpose: This work investigates the potential benefit of adaptive planning using the Ethos radiotherapy system (Varian Medical Systems) with direct-dose calculation on HyperSight cone beam CT (CBCT) f...
Authors: Doris Dimitriadis/Dimitriadou, Denisa R. Goia, M. Saiful Huq, Ronald John Lalonde, Noor Mail, Adam Olson, Tyler Wilhite
Affiliation: UPMC Hillman Cancer Center, UPMC Hillman Cancer Center and University of Pittsburgh School of Medicine, UPMC
Abstract Preview: Purpose: The goal of the HyperSight® offline adaptive-workflow is to create a methodical approach to adaptive-radiotherapy (ART) that considers modifications in patient setup and anatomy. Through effi...
Authors: Xiangli Cui, Lingling Liu
Affiliation: Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, Hefei Cancer Hospital, Chinese Academy of Sciences
Abstract Preview: Purpose:
Respiratory motion introduces substantial dose uncertainties in lung cancer radiotherapy, particularly affecting dose distribution in Simultaneous Integrated Boost-Stereotactic Body Radiot...
Authors: Minbin Chen, Gang Liu, Manju Liu, Weiwei Sang, Pulin Sun, Mingyuan Ye, Fang-Fang Yin, Lihua Zhang, Haiming Zhu
Affiliation: Jiahui International Hospital, Radiation Oncology, Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Medical Physics Graduate Program, Duke Kunshan University, Duke Kunshan University, The First People's Hospital of Kunshan
Abstract Preview: Purpose: This study aims to evaluate the effects of varying the number of arcs on treatment plans created using Volumetric Modulated Arc Therapy (VMAT) for Lattice radiotherapy (LRT).
Methods: Thre...
Authors: Awens Alphonse, Nebi Demez, Michael Kasper, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Tino Romaguera, Hina Saeed, Nishan Shrestha, Somol Sunny
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: In radiation therapy, patient setup errors have been a primary concern impacting dose delivery accuracy. A robust treatment plan is essential to mitigate these errors. This study aimed to eva...
Authors: Mauricio Acosta, Zachary Fellows, Alonso N. Gutierrez, Noah S. Kalman, Kristen A. McConnell, Rob Rohe, Andrew J. Wroe, Sreenija A Yarlagadda
Affiliation: Miami Cancer Institute, Baptist Health South Florida
Abstract Preview: Purpose:
Beam selection is crucial in proton therapy to ensure optimal physical and biological dose conformity to the target while maximizing sparing of normal tissue. This work investigates the im...
Authors: Takahiro Kato, Teiji Nishio, Masataka Oita, Robabeh Rahimi, Yuki Tominaga, Yushi Wakisaka
Affiliation: University of Maryland, Department of Radiological Sciences, School of Health Sciences, Fukushima Medical University, Medical Co. Hakuhokai, Osaka Proton Therapy Clinic, Medical Physics Laboratory, Division of Health Science, Osaka University Graduate School of Medicine, Faculty of Interdisciplinary Science and Engineering in Health Systems, Okayama University
Abstract Preview: Purpose: This study evaluated dose verifications and lateral penumbra improvements for scanned proton therapy plans with and without a multi-leaf collimator (MLC) under various air gaps.
Methods: E...
Authors: Marwa Y. Abdel Tawwab, Amin E Amin, Abdullah M. ElSharif, Somaia Metwally Elsayed, Magdy M. Khalil
Affiliation: School of Applied Health Science, Badr University in Cairo (BUC), Cairo, Egypt, Medical Physics, Radiation Oncology Department, Faculty of Medicine, Ain Shams University, Medical Biophysics, Department of Physics, Faculty of Science, Helwan University
Abstract Preview: Purpose: Prostate cancer radiotherapy typically employs conventional fractionation schedules over approximately eight weeks. This study investigates the effect of variations in the α/β ratio on dose c...
Authors: Nobuki Imano, Daisuke Kawahara, Akito S Koganezawa, Yuji Murakami, Ikuno Nishibuchi, Takuya Wada
Affiliation: Department of Information and Electronic Engineering, Faculty of Science and Engineering, Teikyo University, Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University
Abstract Preview: Purpose: Adaptive radiotherapy (ART) compensates for treatment plans based on anatomical changes while not considering biological effects such as interruptions during treatment. This study aims to dev...
Authors: Asma Amjad, Renae Conlin, Eric S. Paulson, Christina M. Sarosiek
Affiliation: Department of Radiation Oncology, Medical College of Wisconsin
Abstract Preview: Purpose:
MR-guided adaptive radiation therapy (MRgART) is transforming clinical workflows, requiring fast, accurate organs-at-risk (OARs) contouring. While deep learning auto-segmentation (DLAS) of...
Authors: Karyn A Goodman, Yang Lei, Tian Liu, Pretesh Patel, Jing Wang, Kaida Yang, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: This study aims to improve organ-at-risk (OAR) segmentation in pancreatic cancer stereotactic body radiotherapy (SBRT) by integrating clinical guidelines into deep learning workflows. We use ...
Authors: Shahed Badiyan, Chien-Yi Liao, Mu-Han Lin, Dan Nguyen, Justin D. Visak, Hui Ju Wang, Brien Timothy Washington, Kenneth Westover, Yuanyuan Zhang
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Knowledge-based planning (KBP) plays a crucial role in improving treatment plans by leveraging previous clinical data to guide new cases. KBP is applied to the Ethos 2.0 Intelligent Optimizat...
Authors: Ryan Clark, Jon Cornelisse, Kenny Guida, Anthony Magliari, Lesley Rosa, Megan Smith, Shane R Stecklein
Affiliation: Office of Medical Affairs, Varian, A Siemens Healthineers Company, Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Post-mastectomy radiation therapy (PMRT) can pose a challenge for planners of all levels of experience. For cases where 3D conformal therapy yields undesirable results (i.e., dose heterogenei...
Authors: Chloe Min Seo Choi, Joseph O. Deasy, Jue Jiang, Sudharsan Madhavan, Nikhil Mankuzhy, Nishant Nadkarni, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu
Affiliation: University of Freibrug, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose: Voxel-based analysis (VBA) requires accurate topology-preserving inter-patient deformable image registration (DIR). This study assessed whether guiding a DIR method with geometric priors of t...
Authors: James Irrer, Charles K. Matrosic, Martha M. Matuszak, Charles S. Mayo, Kelly C. Paradis, Joann I. Prisciandaro, Benjamin S. Rosen, John Yao, Claire Zhang
Affiliation: University of Michigan, Department of Radiation Oncology, University of Michigan
Abstract Preview: Purpose: To introduce an in-house developed tool, BioDoseUI, designed to calculate and visualize 3D equieffective dose (EQD2Gy) for treatment planning systems (TPS) without such capabilities, to facil...
Authors: Awens Alphonse, Nebi Demez, Noufal Manthala Padannayil, Shyam Pokharel, Suresh Rana, Lauren A. Rigsby, Gagandeep Saini, Nishan Shrestha, Somol Sunny
Affiliation: Lynn Cancer Institute, Boca Raton Regional Hospital, Baptist Health South Florida
Abstract Preview: Purpose: This study examined the impact of varying the pitch factor in hippocampal-avoidance whole-brain (HP-WB) radiotherapy treatments, utilizing the newly introduced VOLO Ultra optimization for Hel...
Authors: Jimmy Caudell, Eduardo G. Moros, Nour Nasser, Gage H. Redler, George Yang
Affiliation: Moffitt Cancer Center
Abstract Preview: Purpose: Dosimetric evaluation of PTV margin reduction for Head and Neck(H&N) sequential boost plans using the Ethos online adaptive radiotherapy(oART) system to investigate the tradeoff in decreased ...
Authors: Andres Portocarrero Bonifaz, Ian Schreiber
Affiliation: CARTI Cancer Center
Abstract Preview: Purpose: To explore how calculation grid resolution, along with other planning factors, affects head and neck dose calculation accuracy and contributes to potential discrepancies in the Eclipse Treatm...
Authors: Nicole C. Detorie, Steven M. Kirsner, Remy Y. Manigold
Affiliation: Scripps Cancer Center
Abstract Preview: Purpose:
Dosimetric Leaf Gap (DLG) is an important factor in obtaining the proper beam model in the Eclipse treatment planning system. The purpose of this study was to investigate the dosimetric im...
Authors: Shen Fu, Zhangmin LI, Zuofeng LI, Yuanshui Zheng
Affiliation: GuangZhou Concord Cancer Center, Guangzhou Concord Cancer Center
Abstract Preview: Purpose: To investigate the influence of different robustness optimization strategies and parameters in proton therapy plans for head and neck tumors on target coverage and OAR (organ at risk) sparing...
Authors: Nesrin Dogan, Panagiota Galanakou, Robert Kaderka
Affiliation: University of Miami, Sylvester Comprehensive Cancer Center, University of Miami Sylvester Comprehensive Cancer Center
Abstract Preview: Purpose:
To develop knowledge-based treatment planning (KBP) for volumetric modulated arc therapy (VMAT) in chest wall treatments with regional nodal involvement. Given the challenges posed due to ...
Authors: Mojtaba Behzadipour, Suman Gautam, Tianjun Ma, Ikchit Singh Sangha, Bongyong Song, William Song, Kumari Sunidhi
Affiliation: UC San Diego, Virginia Commonwealth University
Abstract Preview: Purpose: This study aims to develop a knowledge-based voxel-wise dose prediction system using a convolutional neural network (CNN) for high-dose-rate (HDR) prostate brachytherapy and to evaluate its p...
Authors: Hassan Bagher-Ebadian, Anthony J. Doemer, Ryan Hall, Joshua P. Kim, Bing Luo, Benjamin Movsas, Humza Nusrat, Kundan S Thind
Affiliation: Department of Physics, Toronto Metropolitan University, Henry Ford Health
Abstract Preview: Purpose: This study investigates the development and feasibility of local LLM-based agents to automate radiotherapy treatment planning, aiming to improve planning efficiency and consistency, while pre...
Authors: Yang Sheng, Qingrong Jackie Wu, Qiuwen Wu, Xin Wu, Dongrong Yang
Affiliation: Duke University Medical Center
Abstract Preview: Purpose:
This study aims to leverage large language model (LLMs) to develop a human-in-the-loop agentic framework, enhancing the efficiency of treatment planning in radiotherapy.
Methods:
A L...
Authors: Xianjin Dai, PhD, Wu Liu, Eric Nguyen, Lei Xing, Lewei Zhao
Affiliation: Department of Radiation Oncology, University of California, Los Angeles, Department of Radiation Oncology, Stanford University
Abstract Preview: Purpose: Recent developments in hybrid quantum solvers, which combine quantum and classical processing, enable greater flexibility to tackle problems outside the limited scope of pure quantum computin...
Authors: Shahed Badiyan, Chien-Yi Liao, Mu-Han Lin, David D.M. Parsons, Justin D. Visak, Brien Timothy Washington, Kenneth Westover, Yuanyuan Zhang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX
Abstract Preview: Purpose: Adaptive radiotherapy (ART) programs are resource-intensive due to their technical complexities, requiring highly skilled planners. Leveraging integrated automated treatment planning system (...
Authors: Caroline Chung, Michael Knopp, Stephen F. Kry, Hunter S. Mehrens, John Rong
Affiliation: The University of Texas MD Anderson Cancer Center, UT MD Anderson Cancer Center, University of Cincinnati
Abstract Preview: Purpose: To evaluate the variability of CT dose index (CTDIvol) and radiomics features across a large cohort of radiotherapy simulation CT scans from multiple institutions.
Methods: Three IROC phan...
Authors: Ming Chao, Thomas Chum, Tenzin Kunkyab, Yang Lei, Tian Liu, Richard G Stock, Hasan Wazir, Junyi Xia, Jiahan Zhang
Affiliation: Icahn School of Medicine at Mount Sinai
Abstract Preview: Purpose:
This study aims to develop effective strategies for multi-organ segmentation of pelvic cone-beam computed tomography (CBCT) images based on transformer models to facilitate adaptive radiat...
Authors: Steve B. Jiang, Mu-Han Lin, Yu-Chen Lin, Austen Matthew Maniscalco, Dan Nguyen, David Sher, Xinran Zhong
Affiliation: Medical Artificial Intelligence and Automation (MAIA) Lab & Department of Radiation Oncology, UT Southwestern Medical Center, Medical Artificial Intelligence and Automation (MAIA) Lab, Department of Radiation Oncology, UT Southwestern Medical Center, UT Southwestern Medical Center, Department of Radiation Oncology, UT Southwestern Medical Center, UT Dallas
Abstract Preview: Purpose:
Sequential boost radiotherapy (RT) poses a challenge in allocating dose across multiple plans while protecting organs at risk (OARs). Clinicians must decide whether OAR sparing should occu...
Authors: Gregory Bolard, Rabten Datsang, Sarah Ghandour, Timo Kiljunen, Pauliina Paavilainen, Sami Suilamo, Katlin Tiigi
Affiliation: Turku University Hospital, Virginia Commonwealth University, MVision AI, North Estonia Medical Centre, Docrates Cancer Center, Hopital Riviera-Chablais
Abstract Preview: Purpose: To verify the performance of a vendor-neutral deep learning model for synthetic CT generation from T2-weighted and balanced steady-state MR sequences to support both MR-only simulation and MR...
Authors: Yeona Cho, Chloe Min Seo Choi, Joseph O. Deasy, Jue Jiang, Jihun Kim, Jin Sung Kim, Nikhil Mankuzhy, Aneesh Rangnekar, Andreas Rimner, Maria Thor, Harini Veeraraghavan, Abraham Wu
Affiliation: University of Freibrug, Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Department of Radiation Oncology, Yonsei Cancer Center, Heavy Ion Therapy Research Institute, Yonsei University College of Medicine, Department of Radiation Oncology, Gangnam Severance Hospital, Yonsei University College of Medicine, Memorial Sloan Kettering Cancer Center, Yonsei University
Abstract Preview: Purpose: We hypothesized that combining clinical, imaging, and radiotherapy dose-distribution features could increase predictive model accuracy in radiation-induced severe acute esophagitis (SAE) in e...
Authors: Amy Fitzpatrick, Kim Howard, Julius G. Ojwang, Neelu Soni
Affiliation: Mercy Hospital Springfield
Abstract Preview: Purpose: This study evaluates the dosimetric advantages and workflow improvements of the CyberKnife S7 Precision Treatment Planning System (TPS) with the VOLO optimizer for stereotactic radiosurgery (...
Authors: Zhongjie Lu
Affiliation: Department of Radiation Oncology, The First Affiliated Hospital, Zhejiang University School of Medicine
Abstract Preview: Purpose: Patients with locally-advanced head and neck squamous cell carcinomas(HNSCCs), particularly those related to human papillomavirus(HPV), often achieve good locoregional control(LRC), yet they ...
Authors: Chia-Lung Chien, Wen C. Hsi, Faraz Kalantari, Pouya Sabouri, Man Yam
Affiliation: Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)
Abstract Preview: Purpose:
Reducing treatment delivery time is critical to improving patient throughput and minimizing the risk of intrafraction motion, which can compromise treatment accuracy. This study identifies...
Authors: Panagiotis Iliopoulos, Marios Myronakis, Kyriaki Theodorou
Affiliation: Medical Physics Department, Medical School, University of Thessaly
Abstract Preview: Purpose: To estimate individualized absorbed dose at Organs at Risk (OARs) from kV Cone Beam CT (CBCT) imaging in the pelvic area, prior radiotherapy, and assess excess risk for secondary malignancies...
Authors: Malvern Madondo, Mark McDonald, Zhen Tian, Christopher Valdes, Ralph Weichselbaum, Xiaofeng Yang, David Yu, Jun Zhou
Affiliation: Department of Radiation & Cellular Oncology, University of Chicago, University of Chicago, Emory University, Department of Radiology, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Head-and-neck (HN) cancer patients often experience significant anatomical changes during treatment course. Proton therapy, particularly intensity-modulated proton therapy (IMPT), is sensitiv...
Authors: Jian Chen, Qiufen Guo, Aihua Li, Jing Liu, Junjie MA, Qian WU, Haonan Xiao, Peng Xie, Xiaohui Yan, Yong Yin, Zhe Zhang
Affiliation: Department of Radiation Oncology, Peking University Shenzhen Hospital, Department of Radiation Oncology and Physics, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Department of Obstetrics and Gynaecology, Liao Cheng People’s Hospital
Abstract Preview: Purpose: Online Adaptive radiation therapy (ART) has been an effective technique to manage patient’s inter-fractional anatomical changes and therefore reduces planning target volume (PTV). However, on...
Authors: Nadège Anizan, David Broggio, Désirée Deandreis, Didier Franck, Camilo Garcia, Stéphanie Lamart, Sébastien Leygnac, Alexandre Pignard
Affiliation: Gustave Roussy, Service de Physique Médicale, Institut Bergonié, Service de Physique Médicale, Gustave Roussy, Service de Médecine Nucléaire, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS/LEDI, Autorité de Sûreté Nucléaire et de Radioprotection (ASNR), PSE-SANTE/SDOS
Abstract Preview: Purpose: This work aimed at developing an innovative workflow for 177Lu-PSMA personalized dosimetry to lesions and organs at risk (OAR) simultaneously, considering the cross-irradiation from bone meta...
Authors: Michael Bowers, Patrik Brodin, Madhur Garg, Rafi Kabarriti, William P. Martin, Todd R. McNutt, Julie Shade, Wolfgang A. Tomé, Christian Velten
Affiliation: Johns Hopkins University, Oncospace, Inc., Montefiore Medical Center
Abstract Preview: Purpose: Development of an automated planning tool utilizing AI generated patient-specific dose-volume histogram predictions for rapid H&N plan generation.
Methods: Planning best-practices were dev...
Authors: Sarah Aubert, Leigh Conroy, Tony Tadic
Affiliation: Princess Margaret Cancer Centre
Abstract Preview: Purpose: Cardiac radioablation is an emerging non-invasive treatment option for patients with refractory or life-threatening ventricular tachycardia (VT), however it is difficult to deliver highly con...
Authors: Laura Buchanan, Samantha G. Hedrick, Stephen L. Mahan, Isabella Pfeiffer, Chester R. Ramsey, Taylor Ransom
Affiliation: Thompson Proton Center, University of Tennessee
Abstract Preview: Purpose: Proton pencil beam scanning can reduce normal tissue dose but is highly sensitive to setup, anatomical changes, and range variations. These uncertainties may compromise target coverage and or...
Authors: Ali Hosni, Oleksii Semeniuk, Andrea Shessel, Teo Stanescu
Affiliation: Princess Margaret Hospital, Princess Margaret Cancer Centre, Brown University Health
Abstract Preview: Purpose: To report on early clinical experience with a two-phase radiotherapy approach for esophageal cancer patients, utilizing CBCT-based conventional C-arm linear accelerator radiotherapy and MR-gu...
Authors: Katja M. Langen, Mark McDonald, Bill Stokes, Yinan Wang, Suk Whan (Paul) Yoon
Affiliation: Emory University, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Effective dose management in high-risk re-irradiation (ReRT) patients entails early, detailed special physics consultation (SPC) to mitigate risks from cumulative radiation dose. SPCs have tr...
Authors: Eduardo Florian, Osmar Obdulio Hernandez, Otto Hurtarte, Milton Ixquiac, Erick Orlando Montenegro, Franky Eduardo Reyes, Edgar Aparicio Ruiz, Kevin Vega, Vicky de Falla
Affiliation: Liga Nacional Contra el Cancer, Liga Nacional Contra el Cancer/INCAN, Liga Nacional Contra el Cancer / INCAN, Liga Nacional Contra el Cancer and Universidad de San Carlos de Guatemala, Liga Nacional Contra el Cáncer / INCAN
Abstract Preview: Introduccion:
Lattice Radiation Therapy (LRT) is a form of spatially fractionated radiation therapy (SFRT) designed to improve control of large tumors by delivering ablative doses while minimizing ...
Authors: Mireille Conrad, Cédric De Marco, Marie Fargier-Voiron, Maud Jaccard, Oscar Matzinger, Nicolas Joel Lionel Perichon
Affiliation: Clinique De Genolier
Abstract Preview: Purpose: The Accuray Synchrony real-time motion fiducial tracking solution allows for prostate stereotactic treatment on both Cyberknife and Radixact machines. In our radiotherapy department, two solu...
Authors: Gueorgui Gueorguiev, Kavya Thaniyarasu
Affiliation: University of Bologna, National Centre of Radiobiology and Radiation Protection
Abstract Preview: Purpose: This study investigates the clinical viability of double scattering proton therapy treatment planning for thoracic malignancies using single or multiple treatment fields. The aim of this stud...
Authors: Chih-Wei Chang, Kristin A Higgins, Xiaojun Jiang, Pretesh Patel, Justin R. Roper, Keyur Shah, Sibo Tian, Zhen Tian, Yinan Wang, Xiaofeng Yang, Jun Zhou
Affiliation: Department of Radiation Oncology, City of Hope Cancer Center Atlanta, Emory University, University of Chicago, Department of Radiation Oncology and Winship Cancer Institute, Emory University
Abstract Preview: Purpose: Ventricular tachycardia (VT) is a life-threatening arrhythmia commonly treated with catheter ablation; however, some cases remain refractory to conventional treatment. Stereotactic arrhythmia...
Authors: Chih-Chiang Chang, Chingyun Cheng, Ben Durkee, Minglei Kang, Elissa Khoudary, Yangguang Ma, Xuanqin Mou, YuFei Wang, Tengda Zhang, Wang Zhengda
Affiliation: Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Department of Radiation Oncology, The First Affiliated Hospital of Zhengzhou University, School of Software Engineering, Xi’an Jiaotong University, School of information and communications engineering, Faculty of electronic and information engineering, Xi’an Jiaotong University, Department of Medical Physics, Columbia University, University of Pennsylvania, Department of Human Oncology, University of Wisconsin-Madison
Abstract Preview: Purpose: This study presents a voxel-based analysis method based on deformable image registration to accurately quantify respiratory-induced motion and deformation of both targets and organs at risk (...
Authors: Chloe DiTusa, Panayiotis Mavroidis, Christopher W. Schneider, Sotirios Stathakis
Affiliation: Louisiana State University, Mary Bird Perkins Cancer Center, University of North Carolina
Abstract Preview: Purpose:
To calculate radiobiological metrics of daily dose delivered for head and neck (HN) patients using the daily cone beam CT (CBCT) to generate a pseudo CT (pCT). Moreover, this work compares...
Authors: Daisuke Kawahara, Takaaki Matsuura, Yuji Murakami, Ryunosuke Yanagida
Affiliation: Hiroshima High-Precision Radiotherapy Cancer Center, Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Department of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima
Abstract Preview: Purpose: In recent years, automation in radiation therapy planning using AI has gained significant attention to reduce the workload of treatment planners. Adaptive Radiation Therapy (ART), as a new fo...
Authors: Dante PI Capaldi, Lu Jiang, Qihui Lyu, Ke Sheng
Affiliation: Department of Radiation Oncology, University of California at San Francisco, Department of Radiation Oncology, University of California, San Francisco
Abstract Preview: Purpose:
Preclinical small animal studies help understand radiation-induced biological responses, toxicities, and mechanisms, facilitating the translation of new therapies to patient treatment. Int...
Authors: Laura Buchanan, Samantha G. Hedrick, Stephen L. Mahan, Isabella Pfeiffer, Chester R. Ramsey
Affiliation: Thompson Proton Center
Abstract Preview: Purpose: Linear energy transfer (LET) and variable relative biological effectiveness (RBE) evaluation are important steps in the future of proton therapy, moving beyond RBE=1.1 for all treatment plann...
Authors: William T. Hrinivich, Junghoon Lee, Lina Mekki
Affiliation: Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins University, Department of Biomedical Engineering, Johns Hopkins University, Johns Hopkins University
Abstract Preview: Purpose: Volumetric modulated arc therapy (VMAT) planning is a computationally expensive process. In this work, we propose a reinforcement learning (RL) framework to automatically optimize dose rate a...
Authors: Adebayo Abe, Samuel Olaolu Adeneye, Eben Aje, Bidemi I. Akinlade, Inioluwa Damilola Ariyo, Lilian Ekpo, Muhammad Habeebu, Adedayo O. Joseph, Charles S. Mayo, Noah Ndianaobong, Ikechi S Ozoemelam, Margaret Dideolu Taiwo, Godwin Uwagba
Affiliation: University of Michigan, University of Ibadan, University of Lagos, Missouri University of Science and Technology, NSIA-LUTH Cancer Center, University of Lagos, NSIA-LUTH Cancer Centre, NSIA-LUTH Cancer Center
Abstract Preview: Purpose:
Head and neck cancers (HNC) present significant challenges in radiotherapy due to complex anatomy and the proximity to critical organs at risk (OARs). These challenges are compounded in na...
Authors: Hao Gao, Qiang Li, Yuting Lin, Wei Wang, Wei Wu, Weijie Zhang
Affiliation: Institute of Modern Physics, Chinese Academy of Sciences, China, Department of Radiation Oncology, University of Kansas Medical Center
Abstract Preview: Purpose: Carbon minibeam radiation therapy (cMBRT) offers high peak-to-valley dose ratio (PVDR) and relative biological effectiveness. A key challenge is balancing uniform target coverage with PVDR pr...
Authors: Rafe A. McBeth, Kuancheng Wang, Ledi Wang
Affiliation: Department of Radiation Oncology, University of Pennsylvania, Georgia Institute of Technology, University of Pennsylvania
Abstract Preview: Purpose:
The integration of AI in clinical workflows presents unprecedented opportunities to enhance treatment quality in radiation oncology, yet it also demands innovative approaches to address th...
Authors: Yijian Cao, Sean T Grace, Marissa Joyce Vaccarelli
Affiliation: Northwell
Abstract Preview: Purpose:
This study investigates the dosimetric efficacy of significantly limiting gantry angles in prostate radiation therapy to as a promising strategy to maintain plan quality while enhancing ma...
Authors: Kim Creach, Kim Howard, Julius G. Ojwang, Richard A. Shaw, Neelu Soni
Affiliation: Mercy Hospital Springfield
Abstract Preview: Purpose: To present a standardized MRI-CT hybrid workflow for High-Dose-Rate (HDR) Image-Guided Adaptive Brachytherapy (IGBT) in cervical cancer, aligned with AAPM TG-303, as a model to assist with im...
Authors: Brian M. Anderson, Simon A. Brundage, Xuguang Scott Chen, Shiva K. Das, Felice Dong, Spencer Lynch, Panayiotis Mavroidis, Ryan Morse Morse, Heidi Urquidi
Affiliation: University of North Carolina Chapel Hill, University of North Carolina at Chapel Hill, University of North Carolina
Abstract Preview: Purpose: This study aims at correlating different dosimetric indices of nodal GTV with the regional recurrencies observed after head and neck radiotherapy. Also, to perform a tumor control probability...
Authors: Wen C. Hsi, Tae Kyu Lee, Biniam Yo Tesfamicael
Affiliation: Allina Health, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS), Oklahoma Proton Center
Abstract Preview: Purpose: When minimal dose-variations induced by inter-fractional anatomical-changes and positioning-deviation were found for having limited impact on clinic-outcomes of oropharyngeal head-and-neck (H...
Authors: Anthony R Bardwell, Dong Won Kim, Faith S Kim, Isaac Y Kim, Juying Zhang
Affiliation: Kaiser Permanente
Abstract Preview: Purpose: When a patient develops a significant skin reaction at some point during postmastectomy radiotherapy, a clinical decision is often made to discontinue the planned daily use of bolus. The aim ...
Authors: Chia-Lung Chien, Renteng Hou, Wen C. Hsi, Faraz Kalantari, Ganesh Narayanasamy, Zhong Su
Affiliation: University of Arkansas for Medical Sciences, Department of Radiation Oncology, University of Arkansas for Medical Sciences (UAMS)
Abstract Preview: Purpose:
PRDR is an effective re-irradiation treatment for patients who have already reached the tolerance dose to their organs at risk (OARs). While PRDR is implemented on TrueBeam by limiting the...
Authors: Kevin Albuquerque, Ti Bai, Yesenia Gonzalez, Brian A. Hrycushko, Zohaib Iqbal, Paul M. Medin, Shanshan Tang
Affiliation: Department of Radiation Oncology, UT Southwestern Medical Center
Abstract Preview: Purpose: Cervical cancer remains one of the most common and significant gynecological (GYN) malignancies globally, often presenting at advanced stages where radiation therapy and high-dose-rate (HDR) ...
Authors: Xiu tong Lin
Affiliation: Department of Radiation physics and technology, Shandong Second Provincial General Hospital
Abstract Preview: Purpose: To compare the dosimetric differences between the photon and proton plans and between the different target according to the placement of the implants for patients undergoing radiotherapy afte...
Authors: Jenny Dankelman, Ben J. M. Heijmen, Inger-Karine K. Kolkman-Deurloo, Remi A. Nout, Linda Rossi, Robin Straathof, Linda Wauben, Henrike Westerveld, Nick J. van De Berg, Sharline M. van Vliet - Perez
Affiliation: Department of BioMechanical Engineering, Delft University of Technology, Department of Gynecological Oncology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Department of Radiotherapy, Erasmus MC Cancer Institute, University Medical Center Rotterdam
Abstract Preview: Purpose:
To quantify the dosimetric advantages of the 3D-printed patient-tailored ARCHITECT applicator with optimized needle channel configurations compared to clinically used intracavitary/interst...
Authors: Shane McCarthy, Damodar Pokhrel, William St. Clair, Eddy S Yang
Affiliation: University of Kentucky, Department of Radiation Medicine
Abstract Preview: Purpose: Demonstrating the feasibility of dose escalation for stereotactic recurrent head and neck (RHN) cancers through the deployment of a Hyper-Arc Based RapidPlan (HARP) model through an Eclipse S...
Authors: Claus Belka, Stefanie Corradini, Christopher Kurz, Guillaume Landry, Matteo Maspero, Adrian Thummerer, Erik van der Bijl
Affiliation: Department of Radiation Oncology, LMU University Hospital, LMU Munich, Radboud University Medical Center, UMC Utrecht
Abstract Preview: Purpose: To automatically harmonize non-standardized organ-at-risk (OAR) structure names from multi-lingual, multi-institutional radiotherapy datasets using state-of-the-art open-source reasoning larg...
Authors: Shira Abraham, Eric Aliotta, Michalis Aristophanous, Laura I. Cervino, Yu-Chi Hu, Phillip G. Lichtenwalner, Chuan Zeng, Pengpeng Zhang
Affiliation: Department of Medical Physics, Memorial Sloan Kettering Cancer Center, Memorial Sloan Kettering Cancer Center
Abstract Preview: Purpose:
We have developed a tool that uses deformable image registrations to perform deformable dose accumulation. In this work we evaluate use of this tool for adaptive head and neck dose accumul...
Authors: Ibrahim Aref, David Bergman, Justine M. Cunningham, Payton Dolan, Aharon Feldman, Yimei Huang, Joshua P. Kim, Brett M. Miller, Emily Moats, Benjamin Movsas, Kundan S Thind
Affiliation: Henry Ford Health
Abstract Preview: Purpose: Cardiac radiation dose is directly associated with adverse cardiac events which are predictive of mortality in lung cancer patients. In fractionated lung radiotherapy, studies have shown a hi...