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deep learning head neck monte carlo organs risk ground truth machine learning computed tomography neural network statistically significant normal tissue online adaptive noise ratio spatial resolution carlo simulations abstractpurpose evaluate standard deviation auto segmentation soft tissue risk oars photon counting intensity modulated significant differences gamma passing stereotactic radiosurgery signal noise dice similarity ptv coverage hdr brachytherapy deformable registration stereotactic body gamma knife organ risk ion chamber abstractpurpose develop linear accelerator spinal cord oar sparing passing rates pass rates decision making breath hold gamma pass risk oar clinically acceptable dosimetric impact end end field size similarity coefficient solid water varian truebeam